What are the effects and recommended dosages of myoinositol (Inositol) for men?

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Last updated: July 8, 2025View editorial policy

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From the Research

Myoinositol supplementation for men is recommended at a dosage of 2-4 grams daily, divided into two doses, to potentially improve sperm parameters, insulin sensitivity, and mental health, as supported by the most recent and highest quality study 1. The effects of myoinositol on men's health are multifaceted, including:

  • Improving sperm parameters such as motility and count, which can enhance fertility 1, 2
  • Supporting insulin sensitivity, which can be beneficial for men with metabolic concerns or insulin resistance 1
  • Potentially supporting mental health by acting as a second messenger in cellular signaling pathways 3 The recommended dosage for men with fertility issues is 2 grams twice daily, as it may improve sperm parameters including motility and count 1, 2. It is essential to note that myoinositol works by supporting cell membrane function and acting as a second messenger in cellular signaling pathways, particularly those involved in insulin action 1. Side effects are generally mild and may include nausea, headache, dizziness, or gastrointestinal discomfort, especially at higher doses 1, 2. Men with diabetes should monitor blood sugar levels when using inositol, as it may enhance insulin sensitivity and potentially affect blood glucose levels 1.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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