Silicone Gel Is the Most Effective Ointment for Preventing Scarring
Silicone gel is the most effective topical treatment for preventing scarring and should be used as first-line therapy for scar prevention.
Mechanism and Evidence for Silicone Gel
Silicone gel works through several mechanisms:
- Creates occlusion and hydration of the stratum corneum
- Modulates cytokine signaling from keratinocytes to dermal fibroblasts
- Normalizes collagen production in healing wounds 1
The evidence supporting silicone gel for scar prevention is strong:
- Silicone gel sheeting has been used successfully for more than 20 years in scar management 1
- Modern silicone gel formulations that form a thin flexible sheet over newly epithelialized wounds are equivalent in efficacy to traditional silicone gel sheeting but easier to use 1
- Clinical studies demonstrate that silicone gel effectively prevents hypertrophic scars and keloids compared to no treatment 2
Application Recommendations
For optimal results:
- Apply silicone gel twice daily to the wound after suture removal 2
- Continue application for at least 2-3 months
- Ensure the area is clean and dry before application
- Allow the gel to dry completely before covering with clothing
Alternative Options
If silicone gel is unavailable or not tolerated, consider these alternatives:
Topical Retinoids:
- Tretinoin cream has shown similar efficacy to silicone gel in preventing hypertrophic scars and keloids 2
- Apply twice daily after suture removal
Salicylic Acid:
- Can be used as a mild keratolytic agent
- Available as 2% salicylic acid ointment BP for combined emollient and mild keratolytic effects 3
- May be used as pretreatment for other scar therapies
Corticosteroid Injections:
- For existing hypertrophic scars or keloids
- Triamcinolone acetonide (10-40 mg/mL) can be injected into hypertrophic scars and keloids 3
- Not preventative but treatment for established problematic scars
Special Considerations
Risk Factors for Abnormal Scarring
Pay particular attention to patients with:
- History of keloid formation (avoid body modifications that puncture the skin) 3
- Family history of keloids
- Darker skin types
- Wounds in high-tension areas (shoulders, chest, back)
Wound Location Considerations
Different body areas may require modified approaches:
- Face: Use silicone gel with extra care to avoid occlusive comedogenic effects
- Joints: Ensure flexibility of the product to allow movement
- Lower extremities: Be cautious as poor healing is a concern in areas below the knee 3
Pitfalls to Avoid
Delayed Treatment:
- Begin scar prevention immediately after wound epithelialization
- Don't wait for abnormal scarring to develop
Inadequate Duration:
- Many patients stop treatment too early
- Continue treatment for at least 2-3 months for optimal results
Unrealistic Expectations:
- Counsel patients that scars cannot be completely eliminated in adults
- Scar prevention reduces the risk of abnormal scarring but doesn't eliminate scarring entirely
Ignoring Sun Protection:
- Newly formed scars are highly susceptible to UV damage
- Recommend sun protection to prevent hyperpigmentation of healing scars
Remember that while silicone gel is the most effective topical treatment for scar prevention, patient adherence to the treatment regimen is crucial for optimal outcomes.