What is the treatment for pneumomediastinum?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 10, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment of Pneumomediastinum

Pneumomediastinum is generally treated conservatively with rest, oxygen therapy, and analgesia, as the air in the mediastinum will be reabsorbed naturally over time. 1

Clinical Overview

Pneumomediastinum is defined as the presence of free air in the mediastinal cavity. It can be categorized as:

  • Secondary pneumomediastinum (with an identifiable cause such as trauma)
  • Spontaneous pneumomediastinum (SPM, without clear etiology)

Diagnostic Evaluation

Before initiating treatment, proper evaluation is essential:

  • Imaging studies:

    • CT scan is the preferred diagnostic tool (100% sensitivity for detecting pneumomediastinum) 2
    • Chest X-ray may miss pneumomediastinum (only 15% detection rate) 2
    • CT can effectively identify patients at high risk for aerodigestive tract injuries (100% sensitivity, 85% specificity) 2
  • Clinical presentation:

    • Severe central chest pain is the main symptom
    • Other symptoms include labored breathing, voice distortion, and subcutaneous emphysema
    • "Hamman's crunch" (crunching sound timed with cardiac cycle) may be present in about 20% of cases 3

Treatment Algorithm

1. For Uncomplicated Pneumomediastinum:

  • Conservative management (primary approach):
    • Rest
    • Supplemental oxygen therapy
    • Adequate analgesia for pain control
    • Observation for 24-48 hours 4

2. For Pneumomediastinum with Suspected Esophageal Origin:

  • Additional measures:
    • Nothing by mouth (NPO status)
    • Prophylactic antibiotics to prevent mediastinitis 5
    • Monitor for signs of mediastinitis or deterioration

3. For Pneumomediastinum with Suspected Major Aerodigestive Injury:

  • Further evaluation needed if CT findings are suspicious:
    • Endoscopic evaluation may be necessary
    • Surgical consultation for potential intervention 2

Important Considerations

  • Most cases of pneumomediastinum resolve within 7 days with conservative management 5
  • Hospitalization length averages 4-13 days (mean 7.8 days) 5
  • Observation alone is appropriate for patients without CT findings suspicious for aerodigestive tract injury 2

Potential Complications to Monitor

  • Tension pneumomediastinum
  • Pneumothorax
  • Mediastinitis
  • Cardiac tamponade-like symptoms due to increased intrapulmonary pressure on venous flow 1

Common Pitfalls to Avoid

  1. Unnecessary invasive procedures: Not all patients with pneumomediastinum require endoscopic evaluation. CT scan can effectively identify those who need further intervention 2

  2. Missing underlying causes: While treating conservatively, consider potential underlying conditions that may have caused the pneumomediastinum (asthma, physical exertion, etc.) 5

  3. Inadequate monitoring: Even with conservative management, patients should be monitored for potential deterioration, especially in the first 24-48 hours

  4. Overlooking the diagnosis: Due to vague presenting symptoms, pneumomediastinum may be misdiagnosed. It should be considered in the differential diagnosis for any patient with unexplained chest pain 3

References

Research

Pneumomediastinum.

Journal of thoracic disease, 2015

Research

Spontaneous pneumomediastinum: time for consensus.

North American journal of medical sciences, 2013

Research

Clinical features of medical pneumomediastinum.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.