Assessment of Mental Status in Intubated Patients
For intubated patients, mental status should be assessed using standardized tools that account for the inability to verbalize, such as the FOUR (Full Outline of UnResponsiveness) score, which evaluates eye responses, motor responses, brainstem reflexes, and respiratory patterns.
Challenges in Assessing Intubated Patients
Intubated patients present unique challenges for mental status assessment due to:
- Inability to speak and provide verbal responses
- Potential confounding effects from sedation and neuromuscular blockade
- Underlying critical illness affecting consciousness
Recommended Assessment Tools
1. FOUR Score (Full Outline of UnResponsiveness)
The FOUR score is particularly valuable for intubated patients as it:
- Does not require verbal response
- Provides more complete assessment of brainstem function 1
- Consists of four components (eye, motor, brainstem, respiration) with each scored 0-4
- Can recognize locked-in syndrome and different stages of herniation 2
- Has excellent interrater reliability (kappa = 0.82) 2
2. Modified Glasgow Coma Scale (GCS)
When using the GCS for intubated patients:
- Document the eye and motor components separately
- Note that the patient is intubated (e.g., "GCS 10T" where T indicates intubation)
- Consider using regression models to estimate verbal score from eye and motor scores when needed 3, 4
3. Richmond Agitation Sedation Scale (RASS) or Sedation-Agitation Scale (SAS)
- Useful for assessing sedation level in intubated patients 1
- Helps distinguish between sedation effects and neurological status
Comprehensive Assessment Approach
Step 1: Optimize Assessment Conditions
- Reduce sedation if clinically appropriate and safe
- Consider a "sedation holiday" or lightening if the patient's condition permits
- Be aware that "wake-up tests" may pose risks in patients with intracranial hypertension 1
Step 2: Perform Systematic Neurological Examination
Eye response assessment:
- Spontaneous eye opening
- Eye opening to voice or pain
- Tracking of objects or examiner
- Pupillary light responses (size, reactivity)
Motor response assessment:
- Response to verbal commands
- Localization to pain
- Withdrawal from pain
- Abnormal flexion (decorticate posturing)
- Abnormal extension (decerebrate posturing)
- No response
Brainstem reflex assessment:
- Pupillary light reflex
- Corneal reflex
- Cough/gag reflex
- Oculocephalic reflex (if no C-spine injury)
Respiratory pattern assessment:
- Breathing pattern if not fully ventilator-dependent
- Respiratory drive
- Patient-ventilator synchrony 1
Step 3: Document Findings Using Standardized Scoring
- Record both the individual components and total scores
- Document confounding factors (sedation, neuromuscular blockade)
- Note time of assessment and any changes from previous examinations
Special Considerations
Sedation Management
- Use short-acting medications like propofol or dexmedetomidine when sedation is necessary 1
- Dexmedetomidine may be preferred as it can reduce ventilation duration and preserve cognitive function 1
- Minimize use of benzodiazepines and opioids which can confound neurological assessment 1
Frequency of Assessment
- Perform baseline neurological assessment before and immediately after intubation 1
- Conduct serial evaluations throughout mechanical ventilation
- Consider more frequent assessments (every 1-4 hours) in patients at high risk for neurological changes 1
Pain Assessment
- Use behavioral pain scales such as the Behavioral Pain Scale (BPS) for non-communicative patients 1
- Recognize that up to 70% of neurocritical care patients can still self-report pain using tools like the Numeric Rating Scale 1
Common Pitfalls and Caveats
Misattribution of sedation effects: Always account for the effects of sedation and neuromuscular blockade when interpreting mental status findings 1
Incomplete documentation: Avoid simply documenting "unable to assess" - instead, record observable components and note limitations
Inconsistent assessment: Use the same assessment tool consistently to allow for meaningful trend analysis
Overlooking subtle changes: Small changes in neurological status may indicate significant clinical deterioration
Failure to use capnography: Waveform capnography should be used for all intubated patients as it can detect many critical incidents before organ damage occurs 1
By using these standardized approaches to mental status assessment in intubated patients, clinicians can more accurately monitor neurological function, detect changes early, and improve patient outcomes.