What is the recommended dosage of Dramamine (dimenhydrinate) for a 22-month-old child with motion sickness?

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Dramamine (Dimenhydrinate) Dosage for a 22-Month-Old Child with Motion Sickness

For a 22-month-old child with motion sickness, dimenhydrinate (Dramamine) should be dosed at 1-2 mg/kg per dose, not exceeding 25 mg per dose, and can be given every 6-8 hours as needed.

Dosage Calculation

For a 22-month-old child:

  • Weight-based dosing: 1-2 mg/kg per dose 1
  • Typical weight of 22-month-old: approximately 10-12 kg
  • Calculated dose range: 10-24 mg per dose
  • Maximum single dose: 25 mg 1
  • Frequency: Every 6-8 hours as needed, not to exceed 3 doses in 24 hours

Administration Considerations

Forms Available:

  • Tablets (50 mg - will need to be divided)
  • Liquid formulation (12.5 mg/5 mL)
  • Chewable tablets (25 mg)

Timing:

  • Administer 30-60 minutes before travel for best preventive effect
  • Can be given with food to reduce gastrointestinal side effects

Safety Precautions

Important Warnings:

  • Dimenhydrinate can cause significant sedation in young children
  • Monitor for paradoxical excitation, which can occur in young children
  • Avoid use for more than 2-3 days without medical supervision

Potential Side Effects:

  • Drowsiness (most common)
  • Dry mouth
  • Blurred vision
  • Urinary retention
  • Constipation
  • Potential for seizures with overdose 2

Monitoring

  • Monitor for excessive sedation
  • Ensure adequate hydration
  • Discontinue if any unusual symptoms develop
  • Watch for signs of overdose: extreme drowsiness, seizures, hallucinations

Alternative Approaches

For children under 2 years, consider non-pharmacological approaches first:

  • Position child to see out the window
  • Ensure good ventilation
  • Frequent stops during car travel
  • Distraction techniques (music, toys)
  • Small, frequent snacks (avoid heavy meals before travel)

Caution

A case report documented seizures in a 13-month-old who received excessive dimenhydrinate dosing (23 mg/kg total over 2 days) 2. This highlights the importance of adhering to recommended dosages and not exceeding the maximum daily amount, especially in young children.

Remember that while dimenhydrinate is commonly used for motion sickness in children, its use in very young children should be approached with caution and for limited duration.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[How safe are dimenhydrinate suppositories?].

Deutsche medizinische Wochenschrift (1946), 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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