What are the causes of bronchoscopic (bronchoscopy) failures?

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Last updated: February 8, 2025View editorial policy

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From the Guidelines

Bronchoscopic failures are primarily caused by inability to manage bleeding, airway obstruction, and difficulty in navigating the bronchoscope due to anatomical abnormalities or excessive secretions.

Causes of Bronchoscopic Failures

  • Bleeding: Hemoptysis, which can be caused by malignant lesions involving the airways, neovascularization, tumor necrosis, or iatrogenic procedures such as bronchoscopy itself 1.
  • Airway Obstruction: Blood clots, tumors, or secretions can obstruct the airway, making it difficult to pass the bronchoscope or maintain a clear airway 1.
  • Anatomical Abnormalities: Congenital or acquired abnormalities, such as tracheal stenosis or mediastinal masses, can make it challenging to navigate the bronchoscope 1.
  • Infection Control: Failure to follow proper infection control measures, such as wearing protective clothing and using adequate ventilation, can lead to the transmission of infectious diseases 1.
  • Technical Difficulties: Difficulty in intubating the patient, inadequate sedation, or equipment failure can also contribute to bronchoscopic failures 1.

Management of Bronchoscopic Failures

In cases where bronchoscopic failures occur, alternative management strategies may be employed, such as:

  • Bronchial Artery Embolization: To control bleeding in cases of massive hemoptysis 1.
  • Surgical Intervention: In cases where bronchoscopic management is not feasible or has failed 1.
  • Videolaryngoscopy: As an alternative to bronchoscopy in cases of difficult airway management 1.

From the Research

Causes of Bronchoscopic Failures

The causes of bronchoscopic failures can be attributed to various factors, including:

  • Mechanical complications related to airway manipulations or bleeding 2
  • Systemic complications arising from the procedure itself, medication administration (primarily sedation), or patient comorbidities 2
  • Lack of expertise or appropriate precautions 3
  • Difficulty in navigating to the lung periphery, avoidance of vasculature structures when performing diagnostic biopsies, and the ability to biopsy a lesion under direct visualization 4
  • Cardio-pulmonary complications, bleeding, and pneumothorax 5
  • Patient's health status, such as heart failure, ischemic heart disease, diabetes mellitus, and hypertension, which can make the procedure more challenging 6

Patient-Related Factors

Patient-related factors that can contribute to bronchoscopic failures include:

  • Comorbidities, such as heart failure, ischemic heart disease, diabetes mellitus, and hypertension 6
  • Fragile nature of critically ill patients 3
  • Inadequacy for conventional anesthesia methods 6

Procedure-Related Factors

Procedure-related factors that can contribute to bronchoscopic failures include:

  • Mechanical complications related to airway manipulations or bleeding 2
  • Systemic complications arising from the procedure itself, medication administration (primarily sedation) 2
  • Lack of expertise or appropriate precautions 3
  • Difficulty in navigating to the lung periphery, avoidance of vasculature structures when performing diagnostic biopsies, and the ability to biopsy a lesion under direct visualization 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Complications of bronchoscopy: A concise synopsis.

International journal of critical illness and injury science, 2015

Research

Interventional Bronchoscopy.

American journal of respiratory and critical care medicine, 2020

Research

Clinical Value of Bronchoscopy in Acute Respiratory Failure.

Diagnostics (Basel, Switzerland), 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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