Stimulation Intensity for Peripheral Nerve Blocks
For peripheral nerve blocks, the recommended stimulation intensity is 0.3-0.5 mA with a pulse width of 100 microseconds to achieve optimal nerve localization while maintaining safety. 1
Optimal Stimulation Parameters
Current Intensity
- Initial setting: Begin with 1.0-2.0 mA to locate the general vicinity of the nerve
- Target range: 0.3-0.5 mA for final needle positioning before injection
- Minimum threshold:
- Extraneural (optimal): 0.3-0.5 mA
- Intraneural (avoid): <0.2 mA
Pulse Width and Frequency
- Standard pulse width: 100 microseconds
- Typical frequency: 1-2 Hz (stimulations per second)
Technical Considerations
Nerve Stimulator Settings
- Polarity: Traditionally cathode-based stimulation is used, though anodic stimulation may be more predictable at near-nerve distances 2
- Current characteristics: Square wave, monophasic pulse
- Maximum voltage output: Varies between devices (7.4-336 Volts) 3
Equipment Variability
- Nerve stimulators vary significantly in accuracy, especially at lower current outputs 3
- At currents of 0.1 mA, error rates can reach 10.4% (-24-180%) 3
- Always check battery status before beginning the procedure
Clinical Application
Approach to Nerve Localization
- Begin with higher current (1-2 mA) to elicit initial motor response
- Gradually decrease current while advancing needle toward nerve
- Final needle position should elicit appropriate motor response at 0.3-0.5 mA
- Caution: Current <0.2 mA suggests intraneural placement and risk of nerve injury
Safety Considerations
- Stimulation at ≤0.5 mA provides a 96.3% success rate, comparable to blocks performed at >0.5 mA 4
- Excessive needle manipulation to achieve very low current thresholds (<0.3 mA) may increase risk of intraneural injection 4
- Avoid stimulation intensities <0.2 mA as this suggests intraneural placement
Special Considerations
Factors Affecting Stimulation Thresholds
- Patient factors: Temperature, peripheral edema, diaphoresis, skin resistance 1
- Anatomical location: Different muscle groups require different stimulation thresholds
- Technical factors: Electrode placement, needle-to-nerve distance, stimulator characteristics
Monitoring Recommendations
- Use ultrasound guidance whenever possible to reduce the risk of local anesthetic systemic toxicity 1
- For deep blocks with higher risk of complications, combining ultrasound with nerve stimulation provides complementary information
Common Pitfalls to Avoid
- Relying solely on current intensity: A successful motor response at low current doesn't guarantee proper needle placement
- Ignoring patient factors: Hypothermia, edema, and neuropathy can alter stimulation thresholds
- Equipment variability: Different nerve stimulators have varying electrical characteristics that affect performance 3
- Excessive pursuit of low current thresholds: Manipulating the needle to achieve very low thresholds (<0.3 mA) may increase risk of nerve injury
The distance-current relationship indicates that at 0.3 mA with a pulse width of 100 microseconds, the needle tip is approximately 5 mm from the nerve, which represents an optimal balance between block success and safety 5.