Treatment of Oral Aphthous Ulcers in Children
Topical anesthetics are the first-line treatment for oral aphthous ulcers in children, followed by topical corticosteroids for persistent cases. 1
First-Line Treatment Options
Topical Anesthetics
- Benzocaine: Can be applied up to 4 times daily in children 2 years and older (children under 12 should be supervised) 2
- Viscous lidocaine 2%: Effective for pain management in ulcerated lesions 3
- Magic mouthwash: Equal parts diphenhydramine, antacid, and viscous lidocaine can provide relief 3
Supportive Care Measures
Oral hygiene:
- Twice-daily gentle toothbrushing
- Chlorhexidine or fluoride oral rinse if toothbrushing is too painful 3
Dietary modifications:
- Avoid crunchy, spicy, acidic foods and hot beverages
- Avoid hard, salty foods and carbonated drinks 4
Second-Line Treatment Options
Topical Corticosteroids
For persistent or severe ulcers that don't respond to anesthetics:
- Dexamethasone elixir (0.5 mg/5 mL): Apply directly to ulcers 3
- Fluocinonide gel 0.05%: Apply to accessible ulcers 3
- Clobetasol gel 0.05%: For more severe cases 3
Protective Agents
- Sucralfate: Forms a protective barrier over ulcers 5
- Coating agents: Help protect the ulcer from further irritation 3
Treatment Algorithm Based on Severity
Mild Aphthous Ulcers
- Topical anesthetics (benzocaine or lidocaine)
- Supportive care (oral hygiene and dietary modifications)
- Follow-up in 7-10 days if not improving
Moderate to Severe Aphthous Ulcers
- Topical anesthetics for immediate pain relief
- Add topical corticosteroids (dexamethasone elixir or fluocinonide gel)
- Consider protective coating agents
- Follow-up within 5-7 days
Special Considerations
When to Suspect Systemic Disease
Consider further evaluation if aphthous ulcers are:
- Persistent beyond 2 weeks 3
- Recurrent (≥4 episodes per year) 5
- Associated with fever, weight loss, or other systemic symptoms
- Multiple or unusually large
Recurrent Aphthous Stomatitis (RAS)
If ulcers recur frequently (≥4 times per year), consider:
- Evaluation for underlying conditions (celiac disease, inflammatory bowel disease, nutritional deficiencies) 5
- More aggressive treatment approach with combined therapies
Common Pitfalls and Caveats
Misdiagnosis: Ensure proper differentiation from herpetic lesions, traumatic ulcers, or manifestations of systemic diseases 3
Inadequate pain control: Pain can significantly affect eating, speaking, and quality of life in children - be aggressive with pain management 4
Overlooking underlying causes: Recurrent aphthous ulcers may be a sign of systemic conditions requiring further investigation 5
Overuse of corticosteroids: Reserve for moderate to severe cases that don't respond to first-line treatments
Inappropriate use in young children: For children under 2 years, consult a dentist or doctor before using topical treatments 2
By following this treatment approach, most oral aphthous ulcers in children will resolve within 7-14 days with minimal complications and improved comfort during the healing process.