What is a good alternative medicine treatment for a psoriatic arthritis flare-up?

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Last updated: July 16, 2025View editorial policy

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Alternative Medicine Treatments for Psoriatic Arthritis Flare-ups

For psoriatic arthritis flare-ups, intra-articular glucocorticoid injections are the most effective alternative medicine treatment option, particularly for localized disease affecting single joints. 1

First-line Alternative Treatments

Local Glucocorticoid Injections

  • Intra-articular steroid injections are highly effective for:
    • Mono/oligoarthritis (few affected joints)
    • Single joint flares in otherwise controlled polyarthritis
    • Dactylitis (sausage digits) via tendon sheath/peritendinous injections
    • Enthesitis (inflammation where tendons/ligaments attach to bone) 1

Cautions with Injections

  • Must be given judiciously to treat persistently inflamed joints
  • Avoid injection through psoriatic plaques
  • Limit repeated injections to the same joint according to clinical judgment 1

Systemic Glucocorticoids

Low-dose systemic glucocorticoids (≤7.5 mg/day of prednisone) may be considered with caution:

  • Registry data shows up to 30% of PsA patients use systemic steroids 1
  • FDA approved for psoriatic arthritis as short-term adjunctive therapy 2
  • Should be used with particular caution if:
    • Patient has severe/extensive skin involvement
    • Patient is not taking concomitant DMARDs 1

Important Risks

  • Potential to cause post-steroid psoriasis flare
  • Not recommended for chronic use
  • Long-term use can lead to major adverse events 1
  • Tapering should be done carefully to avoid skin disease rebound 1

Traditional Chinese Medicine

For patients interested in complementary approaches:

  • Herbal methods may be considered if ingredients are known and well understood
  • Acupuncture has shown relatively minor responses in mild to moderate disease 1
  • Ensure any herbal remedies are used alongside conventional treatments, not as replacements

Coal Tar Preparations

  • Recommended for treating the skin manifestations in mild to moderate psoriasis 1
  • Goeckerman therapy (combination of coal tar and UV light) may be beneficial for certain patients 1

Dietary Approaches

  • Dietary modifications are commonly used by patients to mitigate symptoms 3
  • Omega-3 fatty acid supplements have shown some positive results 3

Treatment Algorithm for Flare Management

  1. For localized joint involvement (1-2 joints):

    • Intra-articular glucocorticoid injections as first choice 1
  2. For more widespread joint involvement:

    • Short course of low-dose systemic glucocorticoids (prednisone ≤7.5 mg/day) with careful monitoring 1
    • Always consider adding or optimizing a DMARD to prevent steroid dependence 1
  3. For skin-predominant flares with joint involvement:

    • Coal tar preparations for skin manifestations 1
    • Cautious use of systemic steroids if skin involvement is severe 1
  4. For patients preferring complementary approaches:

    • Consider well-studied herbal preparations or acupuncture as adjunctive therapy 1, 3
    • Ensure these are used alongside, not replacing, conventional treatments

Important Considerations

  • Alternative treatments should generally be considered adjunctive to disease-modifying drugs
  • The primary goals in PsA treatment are pain reduction, improvement of symptoms, optimization of function, and inhibition of joint damage 4
  • Regular collaboration between dermatologists and rheumatologists yields more optimal control of both skin and joint symptoms 5
  • If alternative approaches are insufficient, progression to conventional DMARDs or biologics may be necessary 1

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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