What are the major key findings in step 2 of ECG (Electrocardiogram) interpretation?

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Last updated: July 17, 2025View editorial policy

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Major Key ECG Findings for Step 2 of ECG Interpretation

In step 2 of ECG interpretation, the key findings to assess are rate, rhythm, axis, intervals, and ST-T wave changes, which are critical for identifying life-threatening conditions that affect morbidity and mortality.

Rate and Rhythm Assessment

  • Heart rate calculation: Determine if bradycardia (<60 bpm) or tachycardia (>100 bpm) is present
  • Rhythm regularity: Assess for regular vs. irregular patterns
  • P wave morphology: Evaluate for presence, consistency, and relationship to QRS complexes
  • Rhythm abnormalities: Identify specific arrhythmias that may require immediate intervention 1

Conduction System Evaluation

  • PR interval: Normal (120-200 ms) vs. prolonged (>200 ms, suggesting AV block) or shortened (<120 ms)
  • QRS duration: Normal (<120 ms) vs. widened (>120 ms, suggesting bundle branch blocks or ventricular rhythms)
  • QT interval: Assess for prolongation (risk of torsades de pointes) or shortening
  • New conduction abnormalities: Compare with previous ECGs when available 1

ST-T Wave Analysis

  • ST elevation: Assess for patterns consistent with STEMI (≥1 mm in two contiguous leads)
  • ST depression: Evaluate for subendocardial ischemia
  • T wave inversions: Note depth, distribution, and symmetry
  • Repolarization changes: Differentiate between ischemic and non-ischemic causes 2

Chamber Abnormalities

  • Left ventricular hypertrophy: Increased QRS voltage with associated ST-T changes
  • Right ventricular hypertrophy: Right axis deviation with tall R waves in right precordial leads
  • Atrial enlargement: P wave abnormalities (duration, amplitude, or morphology) 1

Axis Determination

  • Normal axis: -30° to +90°
  • Left axis deviation: -30° to -90°
  • Right axis deviation: +90° to +180°
  • Extreme axis deviation: -90° to -180° (northwest axis) 1

Clinical Correlation

The ECG findings in step 2 must be interpreted in the clinical context. ST elevation in a patient with active symptoms usually indicates acute occlusion of an epicardial artery requiring emergent reperfusion therapy 2. However, many patients have ST segment elevation due to non-ischemic causes, making clinical correlation essential.

Common Pitfalls to Avoid

  • Over-reliance on computer interpretation: Computer programs have shown lower sensitivity than cardiologists in diagnosing key conditions like LVH (56.6% vs. 63.9%), anterior MI (77.1% vs. 84.9%), and inferior MI (58.8% vs. 71.7%) 3
  • Missing subtle changes: Comparison with previous ECGs is crucial for detecting significant changes
  • Failure to recognize high-risk patterns: Widespread ST depression with ST elevation in aVR may represent diffuse subendocardial ischemia from severe coronary disease requiring urgent intervention 4
  • Ignoring clinical context: ECG interpretation accuracy improves significantly when combined with clinical assessment 5

Systematic Approach for Step 2

  1. Calculate heart rate (normal: 60-100 bpm)
  2. Assess rhythm regularity and P wave morphology
  3. Measure intervals: PR, QRS, QT
  4. Determine axis
  5. Evaluate for chamber enlargement/hypertrophy
  6. Analyze ST-T wave changes for ischemia/injury patterns
  7. Look for conduction abnormalities
  8. Compare with previous ECGs when available 1

This systematic approach to step 2 of ECG interpretation helps identify potentially life-threatening conditions that require immediate intervention, directly impacting patient morbidity and mortality outcomes.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The role of the ECG in diagnosis, risk estimation, and catheterization laboratory activation in patients with acute coronary syndromes: a consensus document.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014

Research

ECG diagnosis and classification of acute coronary syndromes.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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