Recommended Ointment for Laceration Care
For laceration care, mupirocin 2% topical ointment is recommended as the first-line treatment, particularly for minor wounds and secondarily infected skin lesions including lacerations. 1
Evidence-Based Approach to Laceration Care
Topical Antimicrobial Treatment
- Mupirocin 2% topical ointment is specifically recommended in clinical practice guidelines for minor skin wounds and secondarily infected skin lesions, including lacerations 1
- Application instructions:
- Clean the affected area thoroughly first
- Apply a small amount (equivalent to the surface area of a fingertip) to the laceration
- Apply 1-3 times daily
- May be covered with a sterile bandage 2
Wound Management Protocol
Initial wound care:
Wound closure considerations:
Post-closure care:
Important Clinical Considerations
Antibiotic Use
- Topical antibiotics: Wounds heal better with less infection when covered with antibiotic ointment and a clean occlusive dressing 1
- Systemic antibiotics: Not routinely recommended for simple lacerations
Special Populations
- Pediatric patients: Mupirocin 2% topical ointment is also recommended for children with minor skin infections and secondarily infected skin lesions 1
Follow-up Care
- Examine the wound a few days after closure for signs of infection 3
- Sitz baths twice daily until first wound check may be beneficial for certain wounds 1
Pitfalls to Avoid
- Do not apply ice directly to a wound as it can produce tissue ischemia 1
- Avoid using tetracyclines in children under 8 years of age 1
- Do not leave wounds uncovered; occlusive dressings promote faster healing 4
- Avoid excessive tension when closing wounds, which can lead to tissue necrosis and poor healing
The evidence strongly supports that proper wound cleaning, appropriate closure technique, and application of mupirocin 2% topical ointment with proper dressing provides optimal outcomes for laceration care while minimizing infection risk.