How long should I take magnesium glycinate to improve a low magnesium level?

Magnesium Supplementation for Low Magnesium Level of 1.6

For a low magnesium level of 1.6, you should take magnesium glycinate for at least 4-6 weeks with regular monitoring of serum levels until normalization is achieved. Depending on the severity of symptoms and underlying causes, supplementation may need to continue for longer periods.

Dosing Recommendations

• Initial dosing: 320-420 mg of elemental magnesium daily for adults 1
• Administration: Best taken at night when intestinal transit is slowest to maximize absorption 1
• Formulation advantage: Magnesium glycinate is generally better absorbed than inorganic magnesium compounds and causes less gastrointestinal distress 2

Monitoring Schedule

• Check serum magnesium levels after 2-3 weeks of supplementation
• Continue supplementation until levels normalize (>1.8 mg/dL)
• Once normalized, consider maintenance dosing if risk factors for deficiency persist

Factors Affecting Treatment Duration

Several factors may influence how long you need to take magnesium:

1. Severity of deficiency: More severe deficiency (like your level of 1.6) typically requires longer treatment

2. Underlying causes: Addressing the root cause is essential

   • Malabsorption disorders
   • Medication use (diuretics, proton pump inhibitors)
   • Chronic alcohol use
   • Gastrointestinal losses

3. Kidney function: Impaired kidney function may require dose adjustment or alternative treatment approaches 1

Precautions and Considerations

• Avoid in renal insufficiency: If you have kidney problems, magnesium supplementation should be used cautiously as it may lead to hypermagnesemia 1
• Hydration: Ensure adequate hydration while taking magnesium supplements 1
• Potential side effects: Diarrhea is the most common side effect of oral magnesium supplementation; magnesium glycinate tends to cause fewer GI issues than other forms 2, 3

Optimizing Absorption

• Take on an empty stomach or with a small amount of food
• Avoid taking with high-fiber meals or calcium supplements which may decrease absorption
• Consider splitting the dose if taking higher amounts (>300 mg elemental magnesium)

When to Consider Alternative Approaches

If oral supplementation fails to normalize levels after 6-8 weeks:

• Reassess for ongoing losses or malabsorption
• Consider IV magnesium if severe symptomatic hypomagnesemia persists 4
• Evaluate for need of vitamin D supplementation, as vitamin D status can affect magnesium absorption

Remember that magnesium is essential for numerous physiological functions, and restoring normal levels is important for overall health. The time to normalization varies by individual, but most people with mild to moderate deficiency will see improvement within 4-6 weeks of consistent supplementation.