From the FDA Drug Label
Ketoconazole Cream 2% is indicated for the topical treatment of ... in the treatment of tinea (pityriasis) versicolor caused by Malassezia furfur (Pityrosporum orbiculare); Microbiology: Ketoconazole is a broad spectrum synthetic antifungal agent which inhibits the in vitro growth of the following common dermatophytes and yeasts ... yeasts: ... Malassezia ovale (Pityrosporum ovale) and ... Malassezia furfur (Pityrosporum orbiculare).
The treatment for Pityrosporum folliculitis (Malassezia folliculitis) is topical ketoconazole.
- Ketoconazole has been shown to inhibit the growth of Malassezia species, which are responsible for Pityrosporum folliculitis. 1 1
From the Research
Pityrosporum folliculitis (Malassezia folliculitis) is best treated with oral antifungal medications, with a success rate of 92% as reported in the most recent study 2. The treatment of Pityrosporum folliculitis involves targeting the underlying fungal cause of the condition.
- The most effective treatment regimen includes oral antifungal medications, with oral antifungals being the most successful treatment option, achieving a 92% success rate 2.
- Topical antifungal creams and shampoos can also be used in conjunction with oral antifungals to enhance treatment outcomes.
- It is essential to avoid oil-based skincare products, tight clothing, and excessive sweating, as these can worsen the condition by creating an environment favorable for yeast growth.
- If treatment fails, consider possible misdiagnosis or resistant infection requiring alternative antifungals. The condition typically presents with itchy, monomorphic papules and pustules on the upper back, chest, and shoulders, and can be distinguished from acne vulgaris by the presence of fungal spores in the follicular lumen.
- A potassium hydroxide preparation can be used to confirm the diagnosis, and treatment with oral antifungals has been shown to be effective in achieving complete response in most cases 2.
- Maintenance and prevention of recurrence can be achieved through continued use of antifungal shampoos and periodic oral antifungal therapy.