First-Line Treatment for Gingivitis
The first-line treatment for gingivitis is proper mechanical plaque removal through effective brushing technique and interdental cleaning, supplemented by chlorhexidine gluconate oral rinse (0.12%) as an adjunctive therapy for persistent cases. 1, 2
Treatment Algorithm for Gingivitis
Step 1: Mechanical Plaque Control
Toothbrushing: Brush twice daily for at least 2 minutes using proper technique
Interdental Cleaning: Once daily cleaning between teeth
Step 2: For Persistent or Moderate-to-Severe Gingivitis
- Chemical Plaque Control: Add antimicrobial mouthwash
- First choice: Chlorhexidine gluconate (0.12%) rinse twice daily 1
- FDA-approved specifically for gingivitis treatment
- Use 10-15mL for 30-60 seconds, twice daily
- Use between dental visits as part of professional program
- Alternative options (if chlorhexidine causes staining or taste alterations):
- First choice: Chlorhexidine gluconate (0.12%) rinse twice daily 1
Step 3: Professional Intervention
- Professional dental cleaning (scaling) to remove calculus and plaque
- Reinforcement of oral hygiene instructions
- Follow-up to assess improvement
Evidence Strength and Considerations
The strongest evidence supports mechanical plaque removal as the foundation of gingivitis treatment 2. A 2021 randomized controlled trial demonstrated that a comprehensive oral hygiene regimen (stannous fluoride dentifrice, electric toothbrush, antimicrobial rinse, and floss) reduced gingival bleeding by 28-39% compared to usual care over 24 months 4.
Chlorhexidine gluconate (0.12%) has FDA approval specifically for gingivitis treatment and is supported by robust clinical evidence 1. It works by disrupting bacterial cell membranes and reducing plaque formation.
Important Caveats and Pitfalls
- Duration of brushing: While 2 minutes is recommended for general population, patients with gingivitis likely need longer brushing times 2
- Chlorhexidine side effects: Can cause tooth staining, taste alteration, and increased calculus formation with prolonged use
- Compliance issues: Interdental cleaning has low adherence rates; patient education on proper technique and importance is critical
- Systemic considerations: Untreated gingivitis can progress to periodontitis, which has been associated with systemic health issues 5
- Monitoring: Regular follow-up is essential as experimental evidence shows plaque accumulates faster in the presence of gingival inflammation 6
If gingivitis does not improve with these measures, evaluation for underlying systemic conditions (diabetes, immunosuppression) or progression to periodontitis should be considered, as these may require additional interventions.