Criteria for Diagnosing Retropharyngeal Abscess
The diagnosis of retropharyngeal abscess requires a combination of clinical findings, imaging studies, and laboratory tests, with contrast-enhanced CT scan being the gold standard diagnostic modality.
Clinical Presentation
Key Symptoms
- Odynophagia (neck pain) - present in 38% of cases 1
- Fever - present in 17% of cases 1
- Sore throat - present in 17% of cases 1
- Neck mass - present in 16% of cases 1
- Respiratory distress or stridor - less common, only in 5% of cases 1
Physical Examination Findings
- Limitation of neck extension - most common finding (45% of cases) 1
- Torticollis (abnormal neck position) - present in 36.5% of cases 1
- Limitation of neck flexion - present in 12.5% of cases 1
- Purulent drainage in the nose or posterior pharynx 2
- Bulging of the posterior pharyngeal wall
- Neck stiffness 3
- Trismus (limited mouth opening) 3
Imaging Studies
Lateral Neck Radiograph
- Widening of the prevertebral space - most important initial diagnostic finding 4
- Air levels in the retropharyngeal space may be visible 5
Computed Tomography (CT)
- Gold standard for diagnosis 1
- Provides accurate anatomical localization of the abscess 4
- Distinguishes between retropharyngeal abscess and retropharyngeal cellulitis 1
- Helps determine the need for surgical intervention 1
- Used in 63% of cases to verify the presence of an abscess 4
Magnetic Resonance Imaging (MRI)
- May be used in selected cases, especially when evaluating extension to adjacent structures 6
- Particularly useful for abscesses close to the skull base 6
Laboratory Tests
Microbiological Studies
- Cultures from surgical drainage are essential for identifying causative organisms
- Streptococcal species are the most commonly isolated pathogens 6
- Blood cultures should be obtained in all patients 2
- Samples should be sent for both aerobic and anaerobic cultures 2
Other Laboratory Tests
- Complete blood count - typically shows leukocytosis
- C-reactive protein and procalcitonin - may be elevated but not specific for retropharyngeal abscess 2
Diagnostic Algorithm
- Clinical suspicion based on symptoms (odynophagia, fever, neck pain)
- Physical examination focusing on neck mobility limitations and posterior pharyngeal wall examination
- Lateral neck radiograph as initial imaging
- Contrast-enhanced CT scan to confirm diagnosis and determine extent of abscess
- Microbiological sampling during drainage procedure
Common Pitfalls and Caveats
- Respiratory distress and stridor are uncommon presentations despite the proximity to airway 1
- Retropharyngeal abscess can be confused with retropharyngeal cellulitis; CT scan is crucial for differentiation 1
- Nasal cultures correlate poorly with actual abscess cultures and should not be relied upon for diagnosis 2
- Lumbar puncture is relatively contraindicated in suspected deep neck space infections 2
- In children under 5 years, retropharyngeal abscess is typically secondary to upper respiratory infections 4
- In adults, retropharyngeal abscess is often secondary to trauma, foreign bodies (especially fishbones), or dental infections 3, 4
- Delay in diagnosis can lead to serious complications including airway obstruction, mediastinitis, and pulmonary empyema 5
Early diagnosis and appropriate management are critical as retropharyngeal abscess represents a medical-surgical emergency with potentially life-threatening complications if not promptly addressed 3.