Treatment of Stress Headaches
For stress headaches (tension-type headaches), first-line treatment is ibuprofen 400 mg or acetaminophen 1000 mg, which are both effective for pain relief. 1
Pharmacological Treatment Options
First-Line Treatments:
NSAIDs:
Acetaminophen:
Combination Treatments:
- Aspirin + acetaminophen + caffeine combination is highly effective and recommended for more severe stress headaches 1
- This combination may provide better relief than single agents alone 1
Treatment Algorithm Based on Headache Severity
For Mild to Moderate Stress Headaches:
- Start with ibuprofen 400 mg OR acetaminophen 1000 mg
- If inadequate response after 2 hours, can take a second dose (being mindful of daily maximum limits)
- For recurrent headaches, consider adding caffeine to enhance effectiveness
For Moderate to Severe Stress Headaches:
- Use combination therapy (aspirin + acetaminophen + caffeine)
- If ineffective, consider adding a muscle relaxant under physician supervision
- For severe, persistent headaches, consider preventive therapy
Non-Pharmacological Approaches
Physical therapy and rehabilitation interventions have shown benefit for tension-type headaches 1:
- Thermal methods
- Trigger point massage
- Mobilization techniques
- Progressive muscle relaxation
Regular aerobic exercise (2-3 times weekly for 30-60 minutes) can help prevent recurrent stress headaches 1
Prevention for Chronic Stress Headaches
If headaches occur frequently (>15 days/month for 3+ months):
- Amitriptyline (25-100 mg daily) is recommended for prevention 1, 5
- Combined therapy (medication + stress management) provides better outcomes than either treatment alone 5
Important Cautions
- Avoid opioids and butalbital-containing medications for stress headaches as they can lead to dependency, rebound headaches, and eventual loss of efficacy 1
- Limit use of acute medications to no more than twice weekly to prevent medication overuse headache 1
- Monitor for rebound headaches with frequent use of analgesics 1
- Higher doses of acetaminophen (1000 mg) are more effective than lower doses (500-650 mg) 1, 4
Lifestyle Modifications
Addressing underlying stress factors is crucial:
- Regular sleep schedule
- Hydration
- Stress management techniques
- Regular physical activity
- Identification and avoidance of personal triggers
By following this stepped approach to treatment and incorporating both pharmacological and non-pharmacological strategies, most stress headaches can be effectively managed while minimizing the risk of medication overuse and chronic headache development.