What is the treatment for flexor tenosynovitis?

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Last updated: July 25, 2025View editorial policy

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Treatment of Flexor Tenosynovitis

The treatment of flexor tenosynovitis depends on whether it is infectious (pyogenic) or non-infectious, with infectious cases requiring prompt antibiotic therapy and often surgical intervention, while non-infectious cases can be managed with conservative measures including corticosteroid injections.

Diagnosis

Before determining treatment, proper diagnosis is essential:

  • Clinical examination is the cornerstone for detecting tenosynovitis 1
  • Ultrasound can confirm diagnosis with high specificity (80-94%) 2
  • MRI provides detailed imaging of tendon changes with high sensitivity (95%) and specificity (95%) 1

Treatment Algorithm for Flexor Tenosynovitis

1. Infectious (Pyogenic) Flexor Tenosynovitis

Infectious tenosynovitis is a medical emergency requiring prompt treatment:

Early Presentation (Kanavel's signs present for <24-48 hours)

  • First-line treatment:

    • Intravenous antibiotics (targeting Staphylococcus aureus)
    • Elevation and immobilization
    • Close monitoring 3
  • If no improvement within 24-48 hours or worsening symptoms:

    • Surgical drainage and irrigation 4
    • Two-incision technique with catheter irrigation is most common 4

Established/Severe Infection

  • Immediate surgical intervention with:
    • Surgical drainage and irrigation
    • Intravenous antibiotics
    • Consider adding corticosteroids as adjunctive therapy to reduce inflammation and improve range of motion 5

Antibiotic Recommendations

  • Duration: 7-14 days (oral therapy appears effective after initial IV treatment) 6
  • First choice: Amoxicillin + clavulanic acid for oral therapy 6

2. Non-Infectious Flexor Tenosynovitis

Conservative Management

  • Rest and activity modification to prevent ongoing damage 1
  • Ice therapy for 10-minute periods through a wet towel 1
  • NSAIDs for pain relief (oral or topical) 1
  • Splinting to reduce tendon irritation

Corticosteroid Injections

  • Highly effective: Local corticosteroid injections resolve symptoms in approximately 61% of cases after a single injection 7
  • Recurrence: Can be effectively re-treated with additional injections if symptoms return 7
  • Success rate: Nearly 90% of non-infectious cases respond to medical management with corticosteroid injections 7

Surgical Management

  • Reserved for cases that fail conservative treatment
  • Digital flexor tendon tenotomy may be considered for non-rigid hammertoe with nail changes or excess callus 1

Special Considerations

Mycobacterial Tenosynovitis

  • Requires specific antibiotic regimens:
    • For M. terrae complex: Consider macrolide plus ethambutol 1
    • For M. szulgai: Three to four-drug regimen for 12 months 1

Rheumatoid Tenosynovitis

  • Early detection with ultrasound is important as tenosynovitis predicts erosive progression 2
  • Treatment follows rheumatoid arthritis management protocols 1

Potential Complications

  • Tendon adhesions and decreased range of motion
  • Tendon rupture (particularly with repeated corticosteroid injections)
  • Progression to compartment syndrome if untreated
  • Digital ischemia in severe cases

Follow-up

  • Regular monitoring of symptoms and range of motion
  • Hand therapy for patients with residual stiffness
  • Approximately 50% of patients with infectious tenosynovitis require hand therapy after resolution 3

Remember that early diagnosis and appropriate treatment are crucial to prevent long-term complications and preserve hand function, particularly with infectious tenosynovitis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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