From the Research
The recommended dose of suppressive antibiotics for a patient with septum (septal) issues is not explicitly stated in the provided evidence, but based on the most recent and highest quality study, meropenem is a suitable option for the treatment of serious bacterial infections, including those involving the septum, at a dose of 1-2 grams every 8 hours 1. The selection of antibiotics should be based on sound clinical judgement and knowledge of the antimicrobials used, taking into account the type of microorganisms or suspected organism being treated, as well as resistant organisms in both the community and the hospital 2. Some key points to consider when choosing an antibiotic regimen include:
- The principles of rational therapy, which include knowing the type of microorganisms or suspected organism being treated, being familiar with resistant organisms, and initiating combination therapy with a beta-lactam antibiotic plus an aminoglycoside or using monotherapy with either a carbapenem or selected third-generation cephalosporin 2
- The importance of understanding the major pharmacokinetic properties of antibacterial agents for proper use and to minimize the development of resistance 3
- The need for periodic reassessment of the need for ongoing treatment and monitoring for side effects and resistance development 1 It is essential to note that the provided evidence does not specifically address septal issues, and the recommended dose may vary depending on the specific condition and patient population. However, based on the available information, meropenem appears to be a suitable option for the treatment of serious bacterial infections, including those involving the septum.