From the Research
I strongly recommend discontinuing fluconazole as it's unlikely to be treating the underlying cause of your symptoms, and its use without evidence of a fungal infection may contribute to antimicrobial resistance and side effects. Fluconazole is an antifungal medication that should only be used when there's evidence of a fungal infection, which your normal bloodwork suggests you don't have 1. Your symptoms of fatigue and insomnia could be due to various conditions including depression, anxiety, chronic fatigue syndrome, sleep disorders, or nutritional deficiencies.
Potential Causes and Next Steps
Some potential causes of your symptoms include:
- Depression or anxiety
- Chronic fatigue syndrome
- Sleep disorders
- Nutritional deficiencies I suggest consulting with your healthcare provider for a comprehensive evaluation, including a sleep study if insomnia is persistent. In the meantime, focus on sleep hygiene practices such as:
- Maintaining a regular sleep schedule
- Avoiding screens before bedtime
- Limiting caffeine
- Creating a comfortable sleep environment For fatigue management, regular light exercise, proper hydration, and balanced nutrition may help. The perceived improvement with fluconazole could be a placebo effect or coincidental timing with natural symptom fluctuations.
Importance of Evidence-Based Treatment
It's essential to identify and address the true cause of your symptoms, rather than relying on unnecessary antifungal use, which can lead to side effects and contribute to antimicrobial resistance 2, 3, 4, 5. A comprehensive evaluation by your healthcare provider will help determine the underlying cause of your symptoms and guide appropriate treatment.