Differential Diagnosis for Benign Penile Pimples that Discharge White Substance when Squeezed
- Single most likely diagnosis
- Pearly penile papules: These are small, benign growths that can appear on the penis, often around the glans or corona. They are very common and can sometimes discharge a white substance when squeezed, although this is not always the case. They are harmless and do not require treatment unless they cause discomfort or cosmetic concern.
- Other Likely diagnoses
- Fordyce spots: These are small, yellowish or white bumps on the penis (or other parts of the genitals) that can sometimes discharge a white substance. They are benign and represent ectopic sebaceous glands.
- Sebaceous hyperplasia: This condition involves an overgrowth of sebaceous glands, which can appear as bumps or papules on the penis. While less common than pearly penile papules or Fordyce spots, they can also discharge a substance when squeezed.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Penile cancer: Although extremely rare and unlikely to present with the described symptoms, any unusual growth or discharge from the penis should prompt consideration of malignancy to ensure early detection and treatment.
- Sexually transmitted infections (STIs): Certain STIs, like genital warts or herpes, can cause lesions on the penis. While these typically have different characteristics (e.g., painful ulcers, multiple lesions), it's crucial to consider STIs in the differential diagnosis due to their potential for serious health consequences if left untreated.
- Rare diagnoses
- Lichen nitidus: A rare skin condition characterized by tiny, shiny, flat-topped bumps that can appear on the penis among other areas. It's benign but can be itchy or cause discomfort.
- Syringoma: Benign tumors of the sweat glands that can appear as small, firm bumps on the penis. They are rare and usually do not discharge a substance, but could potentially be considered in a differential diagnosis for penile lesions.