Types of Folliculitis That Cause Abscesses
Deep folliculitis, particularly furuncles and carbuncles caused by Staphylococcus aureus, are the main types of folliculitis that progress to form abscesses. 1
Deep Folliculitis Types That Form Abscesses
Furuncles (Boils)
- Infections of hair follicles caused primarily by S. aureus
- Suppuration extends through the dermis into subcutaneous tissue, forming a small abscess
- Clinically present as inflammatory nodules with overlying pustules through which hair emerges
- Differ from superficial folliculitis, where inflammation is limited to the epidermis 1
Carbuncles
- Form when infection involves several adjacent hair follicles
- Create a coalescent inflammatory mass with pus draining from multiple follicular orifices
- Typically larger and deeper than furuncles
- Most commonly develop on the back of the neck
- More likely to occur in individuals with diabetes 1
Folliculitis et Perifolliculitis Capitis Abscedens et Suffodiens
- Rare, severe form of deep folliculitis that forms extensive abscesses
- Characterized by fluctuating painful fistule-forming conglomerates of abscesses
- Often affects the occipital scalp
- Most common in men of African-American or African-Caribbean descent aged 20-40 years 2
Folliculitis Decalvans
- Rare inflammatory condition of the scalp
- Can progress to form painful pustules and abscesses
- Leads to scarring alopecia
- S. aureus is believed to play a role in its development 3
Pathophysiology of Abscess Formation
- In deep folliculitis, infection extends beyond the hair follicle into surrounding tissue
- Suppuration progresses through the dermis into subcutaneous tissue
- Neutrophilic infiltration is the initial histopathologic finding, followed by granulomatous infiltrate 2
- Abscess formation represents a collection of pus within the dermis and deeper skin tissues 1
Risk Factors for Abscess-Forming Folliculitis
- Diabetes mellitus (particularly for carbuncles)
- Impaired immune function, especially neutrophil dysfunction
- Poor circulation from peripheral vascular disease
- Hyperglycemia creating favorable conditions for bacterial growth
- Increased skin colonization with S. aureus 4
- Poor personal hygiene
- Close contact with infected individuals 1
Management of Folliculitis-Associated Abscesses
Treatment Approach
- Incision and drainage is the primary treatment for large furuncles and all carbuncles 1
- Probing the cavity to break up loculations may be necessary 4
- Cover the surgical site with a dry dressing (avoid packing with gauze as it may cause more pain without improving healing) 1, 4
- Systemic antibiotics are usually unnecessary unless there is:
- Fever or other evidence of systemic infection
- Extensive surrounding cellulitis
- Markedly impaired host defenses
- Presence of SIRS (temperature >38°C or <36°C, tachypnea >24 breaths/min, tachycardia >90 beats/min, or WBC >12,000 or <400 cells/μL) 1
For Recurrent Abscesses
- Search for local causes such as pilonidal cyst, hidradenitis suppurativa, or foreign material 1
- Drain and culture early in the course of infection 1
- Consider a 5-day decolonization regimen:
- For persistent recurrent cases, consider clindamycin 150 mg daily for 3 months 4
- Evaluate for neutrophil disorders if recurrent abscesses began in early childhood 1, 4
Common Pitfalls and Caveats
- Needle aspiration of abscesses has low success rates (<25% overall, <10% with MRSA) and is not recommended 1
- Cultures are not routinely needed for typical cases but should be obtained for recurrent abscesses 1, 5
- Simple folliculitis is more superficial and does not typically form abscesses; don't confuse with deeper infections 1
- In diabetic patients, maintain optimal glycemic control to prevent recurrent skin infections 4
- Carbuncles require more aggressive management than furuncles due to their deeper and more extensive nature 1
- Consider MRSA coverage for patients with infections that have not improved with initial treatment 6