Management of Hip and Buttock Pain
The management of hip and buttock pain should follow a multimodal approach starting with conservative measures including exercise therapy, weight management, and non-opioid analgesics, with pharmacological options progressing from topical to oral medications based on pain severity and response to treatment. 1
Initial Assessment and Classification
Hip and buttock pain can be categorized based on location:
- Anterior groin pain: Often indicates intra-articular pathology (osteoarthritis, labral tears)
- Lateral trochanteric pain: Commonly associated with greater trochanteric pain syndrome
- Posterior buttock pain: May indicate piriformis syndrome, sacroiliac joint dysfunction, or referred pain from lumbar spine 2, 3
First-Line Management
Non-Pharmacological Approaches
Self-management program (Weak recommendation) 1
- Regular self-directed exercise
- Weight reduction for overweight/obese patients
- Bracing for knee OA (if applicable)
Physical therapy (Weak recommendation) 1
- Should be offered as part of comprehensive management
- Exercise-based treatments should be at least 3 months in duration
- Should include strengthening of hip, trunk and functional components
Pharmacological Approaches
Topical agents (for knee OA; limited evidence for hip) 1
- Topical NSAIDs (Strong recommendation for knee OA)
- Topical capsaicin (Weak recommendation for knee OA)
Oral medications (Weak recommendation) 1
- Acetaminophen: Starting dose 325-650mg every 4-6 hours (maximum 3000mg/day)
- Oral NSAIDs: Ibuprofen 400-800mg three to four times daily (maximum 3200mg/day) 4
- Use the lowest effective dose for shortest duration to minimize adverse effects
Second-Line Management
For patients with inadequate response to first-line treatments:
Combination pharmacotherapy 1
- Duloxetine as alternative or adjunctive therapy (Weak recommendation for knee OA)
- Consider combining acetaminophen with NSAIDs
Intra-articular injections 1
- Corticosteroid injection for persistent knee pain inadequately relieved by other interventions (Weak recommendation)
- Limited evidence for hip injections
Important Considerations
Avoid opioids (including tramadol) for initial management of hip and buttock pain (Weak recommendation against) 1
Comorbidities assessment before finalizing treatment plan:
- Cardiovascular disease
- Gastrointestinal bleeding risk
- Chronic kidney disease
- Hypertension 1
Complementary approaches (insufficient evidence):
- Acupuncture
- Massage
- Tai chi
- Yoga 1
Treatment Algorithm
Initial approach:
- Self-management with exercise and weight management
- Physical therapy referral
- Topical agents for knee pain (NSAIDs, capsaicin)
- Acetaminophen and/or oral NSAIDs
If inadequate improvement:
- Reassess diagnosis and consider imaging if not previously done
- Intensify physical therapy
- Consider duloxetine as adjunctive therapy
- Consider intra-articular corticosteroid injection (for knee)
For persistent symptoms:
- Obtain weight-bearing radiographs
- Consider surgical consultation if conservative measures fail 1
Common Pitfalls
- Misdiagnosis: Hip pain can be misdiagnosed as lumbar pathology, leading to unnecessary spine interventions 5
- Premature imaging: MRI should be performed only if history and plain radiographs are not diagnostic 3
- Inadequate trial of conservative therapy: Physical therapy should be continued for at least 3 months 1
- Over-reliance on opioids: NSAIDs and acetaminophen should be optimized before considering opioids 1
- Focusing only on pain: Address functional limitations and quality of life 1
By following this structured approach to hip and buttock pain management, clinicians can effectively address symptoms while minimizing risks associated with more invasive interventions.