What is the recommended daily fluid intake for patients with end-stage renal disease (ESRD) on dialysis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 31, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Fluid Management for Patients with Renal Disease on Dialysis

For patients with end-stage renal disease on dialysis, fluid intake should be limited to 1-1.5 liters per day plus the equivalent of urine output to prevent complications related to fluid overload. 1

Understanding Fluid Restrictions in Dialysis Patients

Fluid management is a critical component of care for dialysis patients. Proper fluid balance helps prevent:

  • Excessive interdialytic weight gain
  • Hypertension and cardiovascular complications
  • Pulmonary edema and shortness of breath
  • Dialysis-related complications such as cramping and hypotension

Recommended Fluid Intake Guidelines

The fluid restriction recommendation is based on several key principles:

  • Basic formula: 1-1.5 liters per day + urine output (if any)
  • For anuric patients (no urine output), fluid intake should be limited to 1-1.5 liters/day 1
  • Interdialytic weight gain should ideally be limited to 1-1.5 kg between dialysis sessions 2
  • This typically corresponds to approximately 1 liter of fluid for every 8 grams of salt consumed 3

Sodium and Fluid Relationship

There is a critical relationship between sodium intake and fluid requirements:

  • Patients should restrict sodium intake to less than 2 grams per day (equivalent to 5 grams of salt) 2
  • Patients who restrict salt intake to <6 g/day and drink only when thirsty should gain no more than 0.8 kg/day 3
  • Higher sodium intake increases thirst and leads to greater fluid intake

Monitoring and Assessment

To ensure proper fluid management:

  • Track interdialytic weight gain (should be <1.5 kg between sessions) 1, 2
  • Monitor for signs of fluid overload (edema, shortness of breath, hypertension)
  • Assess predialysis serum sodium levels
  • Patients with high interdialytic weight gain but normal or high predialysis sodium likely need better sodium restriction 3
  • Patients with high weight gain but low predialysis sodium should be assessed for other reasons for fluid intake (high blood glucose, social drinking) 3

Nutritional Considerations

While managing fluid intake, it's important to maintain adequate nutrition:

  • Dietary protein intake should be approximately 1.2-1.3 g/kg body weight/day for peritoneal dialysis patients 1
  • For hemodialysis patients, protein intake should be at least 1.2 g/kg/day
  • Energy intake should be 35 kcal/kg/day for patients under 60 years and 30-35 kcal/kg/day for those over 60 1

Common Pitfalls and Challenges

  • Focusing only on fluid without addressing sodium: Attempts to restrict fluid intake will be futile if sodium intake remains high 3
  • Overly aggressive fluid restriction: May lead to dehydration, hypotension during dialysis, and poor quality of life
  • Inadequate patient education: Patients need clear guidance on fluid content of different foods and beverages
  • Ignoring residual kidney function: Patients with some urine output can have more liberal fluid allowances

Special Considerations

  • Patients with poor tolerance of fluid removal during dialysis may require stricter salt restriction (<5 g/day) 3
  • During hot weather or increased physical activity, fluid allowances may need adjustment
  • Educational interventions have been shown to improve adherence to fluid restrictions 4
  • Patients with concomitant heart failure may require more aggressive fluid management 5

By following these guidelines and working closely with the healthcare team, dialysis patients can better manage their fluid intake to improve outcomes and quality of life.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Sodium in Chronic Kidney Disease

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Reducing sodium intake in hemodialysis patients.

Seminars in dialysis, 2009

Research

Use of an Educational Intervention to Improve Fluid Restriction Adherence in Patients on Hemodialysis.

Nephrology nursing journal : journal of the American Nephrology Nurses' Association, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.