What is the treatment for a wasp sting?

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Wasp Sting Treatment

The initial treatment for a wasp sting should include prompt removal of any stinger (if present) within 10-20 seconds by flicking or scraping, washing the area with soap and water, and applying a cold compress to reduce pain and swelling. 1

Immediate Management

  1. Remove the stinger (if present - note that unlike bees, wasps can sting multiple times without losing their stinger)

    • Use flicking or scraping motion within 10-20 seconds
    • Avoid squeezing or using tweezers which may inject more venom 1, 2
    • Speed of removal is more important than the method 3
  2. Clean the area

    • Wash with soap and water to prevent secondary infection 1
  3. Reduce pain and swelling

    • Apply ice or cold compress to the sting site 1
    • Use over-the-counter pain relievers:
      • Acetaminophen or NSAIDs for pain relief 1
      • Topical lidocaine may help relieve local pain if skin is intact 1
  4. Control itching and allergic reaction

    • Antihistamines are first-line treatment for hives/urticaria 1
    • Standard doses of non-sedating H1 antihistamines:
      • Cetirizine 10mg once daily
      • Loratadine 10mg once daily
      • Fexofenadine 180mg once daily 1

Monitoring for Complications

Watch for signs of anaphylaxis:

  • Flushing, apprehension, syncope
  • Tachycardia, hypotension
  • Difficulty breathing, airway swelling, laryngospasm
  • Vomiting, diarrhea, abdominal cramps
  • Urticaria, angioedema, swelling of eyelids, lips, and tongue 4

Emergency treatment for anaphylaxis:

  • Administer epinephrine immediately as first-line treatment
    • Adults: 0.3-0.5mg intramuscularly in anterolateral thigh
    • Children: 0.01mg/kg (up to 0.3mg) 1, 4
  • Supportive therapy and transport to emergency department 1

Follow-up Care

  • Monitor for signs of secondary infection or delayed healing 1
  • Reevaluate in 48-72 hours if no improvement 1
  • Antibiotics are usually unnecessary unless signs of infection develop 1

Special Considerations

When to seek immediate medical attention:

  • Signs of anaphylaxis (as listed above)
  • Multiple stings (estimated lethal dose is approximately 20 stings/kg) 5
  • Signs of infection (persistent redness, warmth, swelling, or tenderness) 4
  • History of severe reactions to insect stings 1

Referral to allergist recommended for:

  • Patients who have experienced systemic allergic reaction
  • Those who need education about risk of future reactions
  • Candidates for venom immunotherapy (VIT) 1
  • Patients with mastocytosis (found in 3-5% of patients with sting anaphylaxis) 6

Prevention

  • Avoid areas where wasps are commonly found (bushes, eaves, attics, garbage containers)
  • Wear protective clothing when outdoors
  • Avoid wearing brightly colored clothing or flowery prints
  • Have known or suspected nests removed by trained professionals 1

Most wasp stings are self-limiting and resolve within a few hours without treatment, but close monitoring is essential due to the potential for life-threatening anaphylactic reactions 5.

References

Guideline

Insect Bite and Sting Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Bee or Wasp Sting.

Wounds : a compendium of clinical research and practice, 2017

Research

Removing bee stings.

Lancet (London, England), 1996

Research

Hymenoptera stings.

Clinical techniques in small animal practice, 2006

Research

Insect stings: clinical features and management.

Deutsches Arzteblatt international, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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