Best Treatment for a Wasp Sting
The best treatment for a wasp sting includes thorough cleaning with soap and water, applying a medium-potency topical corticosteroid 2-3 times daily, and using oral antihistamines for itch relief. 1
Immediate Management
- Clean the wound thoroughly with soap and water to remove potential contaminants 1
- Apply a medium-potency topical corticosteroid 2-3 times daily to reduce inflammation 1
- Use oral antihistamines for itch relief:
- Non-sedating options (daytime): cetirizine or loratadine
- Sedating options (nighttime): diphenhydramine 1
- For pain relief:
- Apply topical lidocaine if skin is intact
- Take over-the-counter acetaminophen or NSAIDs 1
- Apply cold compresses (never apply ice directly to skin) 1
Monitoring and Warning Signs
Monitor the sting site for 48-72 hours for signs of infection or progression 1. Seek immediate medical attention if you develop:
- Signs of anaphylaxis: flushing, apprehension, syncope, tachycardia, hypotension, convulsions, vomiting, diarrhea, abdominal cramps, airway swelling, laryngospasm, bronchospasm, pruritus, urticaria, angioedema, or swelling of eyelids, lips, and tongue 2
- Signs of infection: persistent redness, warmth, swelling, or tenderness at the sting site 2
- Increasing redness, warmth, swelling, purulent discharge, worsening pain, fever, or systemic symptoms 1
Special Considerations
Anaphylaxis Management
If signs of anaphylaxis develop, emergency treatment with injectable epinephrine is recommended:
- Adult dosage: 0.3-0.5 mg intramuscularly into anterolateral thigh
- Children ≥30 kg: 0.3-0.5 mL intramuscularly into anterolateral thigh 1, 2
Delay in epinephrine administration has been associated with fatal sting reactions, emphasizing the importance of prompt treatment 1.
Prevention of Future Stings
- Avoid wearing brightly colored clothing or flowery prints
- Avoid using strongly scented materials that might attract insects
- Wear long pants, long-sleeved shirts, socks, and shoes when outdoors
- Avoid walking barefoot or with open shoes
- Remove known nests in the vicinity of home (by trained professionals)
- Avoid areas with high uncut grass, weeds, and low brush
- Be cautious near bushes, eaves, and attics 1
Follow-up Care
- Follow up within 24 hours either by phone or office visit 1
- Patients with a history of systemic reactions to insect stings should be referred to an allergist for evaluation for venom immunotherapy and should carry injectable epinephrine 1
Important Caveats
- Unlike bees, wasps can sting multiple times as they do not lose their stinger 3
- Antibiotics are not routinely needed for early, uninfected insect stings but may be considered if signs of infection develop 1
- Rare complications of wasp stings include skin and soft tissue necrosis 4 and rhabdomyolysis (especially with multiple stings) 5
- Do not pluck or squeeze the stinger if present (more common with bee stings than wasp stings), as this may inject more venom into the wounded site 6