Idiopathic Edema: This condition is characterized by intermittent swelling of the hands and feet without an identifiable cause. It is more common in middle-aged women and can be related to hormonal changes.

Hypothyroidism: Swelling of the hands can be a symptom of hypothyroidism due to the accumulation of mucopolysaccharides in the skin.
Menopause: Hormonal fluctuations during menopause can lead to fluid retention and swelling.
Rheumatoid Arthritis: Although more commonly associated with joint pain and swelling, rheumatoid arthritis can cause swelling in the hands.
Lymphedema: This condition involves the abnormal collection of protein-rich fluid in the interstitial tissue, leading to swelling, usually after surgery, radiation, or infection.

Heart Failure: Severe heart failure can lead to peripheral edema, including swelling of the hands, due to fluid buildup.
Renal Failure: Kidney dysfunction can cause fluid retention, leading to swelling.
Deep Vein Thrombosis (DVT): Although DVT typically affects the legs, it can occur in the arms and cause swelling.
Sepsis: Sepsis can cause widespread inflammation and fluid leakage, leading to swelling.

Scleroderma: A chronic autoimmune disease that can cause thickening and hardening of the skin, leading to swelling and limited mobility.
Mixed Connective Tissue Disease: An autoimmune disorder that can cause swelling, skin thickening, and other systemic symptoms.
Eosinophilia-Myalgia Syndrome: A rare condition characterized by muscle pain, eosinophilia, and sometimes swelling.
Amyloidosis: A group of diseases caused by abnormal protein deposits, which can lead to swelling and other systemic symptoms.