Management of Nabothian Cysts
Nabothian cysts are benign cervical lesions that typically require no treatment unless they become symptomatic or unusually large.
What Are Nabothian Cysts?
Nabothian cysts are mucus-filled retention cysts that form on the cervix when squamous epithelium blocks the opening of nabothian glands, causing mucus accumulation. They are:
- Common in women of reproductive age
- Usually small and asymptomatic
- Typically discovered incidentally during routine pelvic examinations
- Benign lesions with no malignant potential
Diagnostic Approach
When a nabothian cyst is suspected:
- Pelvic examination to visualize the cervix and assess cyst size and location
- Ultrasound is the preferred initial imaging modality for characterization
- MRI may be used for larger cysts to rule out malignancy and determine extent
- Biopsy may be recommended for atypical presentations to exclude malignancy
Management Algorithm
For Asymptomatic Nabothian Cysts:
- No treatment required
- No follow-up imaging necessary
- Patient reassurance about benign nature
For Symptomatic or Large Nabothian Cysts:
Conservative management for mildly symptomatic cysts:
- Observation
- Pain management with appropriate analgesics if needed
Intervention indicated when cysts cause:
Surgical options for symptomatic or large cysts:
Special Considerations
Differential diagnosis: Large nabothian cysts must be differentiated from:
- Adenoma malignum (minimal deviation adenocarcinoma)
- Other cervical malignancies
- Cervical fibroids
- Endometriotic cysts
Unusual presentations: Giant nabothian cysts (>4 cm) may present with:
Imaging pearls: On ultrasound, nabothian cysts appear as:
- Well-defined anechoic or hypoechoic lesions
- May be single or multiple
- No internal vascularity on Doppler
- May appear multiloculated in complex cases 5
Follow-up Recommendations
- No routine follow-up needed for asymptomatic cysts
- For treated symptomatic cysts, one follow-up visit to ensure resolution of symptoms
- No long-term surveillance required after successful treatment
Pitfalls to Avoid
- Misdiagnosing large nabothian cysts as malignant lesions, leading to unnecessary extensive surgery
- Overlooking symptoms caused by large nabothian cysts
- Performing hysterectomy for isolated nabothian cysts when local excision would suffice
- Failing to consider nabothian cysts in the differential diagnosis of cervical masses
Unlike other cystic conditions that may require regular monitoring (such as ovarian cysts or hepatic cysts), nabothian cysts generally follow a benign course and do not require surveillance imaging or follow-up unless they become symptomatic 6, 7.