What are the symptoms of a gastric (peptic) ulcer?

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Last updated: March 5, 2025View editorial policy

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From the Guidelines

Gastric ulcers typically present with burning or gnawing pain in the upper abdomen, often occurring between meals when the stomach is empty or at night, and may be accompanied by other symptoms such as bloating, belching, and nausea, as reported in a recent study 1. The symptoms of a gastric ulcer can vary, but common symptoms include:

  • Burning or gnawing pain in the upper abdomen
  • Bloating and belching
  • Feeling of fullness or heaviness in the abdomen
  • Nausea and vomiting
  • Poor appetite and weight loss
  • Dark, tarry stools (melena) or vomit that resembles coffee grounds, indicating bleeding from the ulcer
  • Heartburn, indigestion, and chest pain These symptoms occur because gastric ulcers are open sores that develop on the stomach lining when protective mucus is reduced or when acid production increases, allowing digestive juices to damage the stomach tissue 1. According to a recent guideline on the management of functional dyspepsia, which can be related to gastric ulcers, patients may also experience symptoms such as pain or burning in the upper part of the abdomen, feeling abnormally full-up early on in a meal, or experiencing a heaviness in the abdomen that may be worse after eating 1. It is essential to seek immediate medical attention if you experience persistent abdominal pain, vomiting blood, dark stools, or severe, sudden abdominal pain, as these may indicate complications such as perforation, bleeding, or obstruction 1.

From the Research

Symptoms of Gastric (Peptic) Ulcer

  • Epigastric discomfort or pain, which can be relieved by food intake or antacids 2
  • Pain that causes awakening at night or occurs between meals 2
  • Loss of appetite 2
  • Weight loss 2
  • Nausea and vomiting 3
  • Epigastric abdominal pain influenced by meals 3

Characteristics of Symptoms

  • Symptoms can be associated with meals 3
  • Pain can be relieved by food intake or antacids 2
  • Symptoms can cause weight loss 2
  • Nausea and vomiting can occur 3

Diagnosis and Treatment

  • Diagnosis is based on upper gastrointestinal fibre endoscopy 3
  • Treatment includes proton pump inhibitors and antibiotics for H. pylori infection 3, 2
  • Symptom relief and ulcer healing can be achieved with proton pump inhibitors 4, 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Peptic ulcer disease.

American family physician, 2007

Research

[Abdominal pain and gastritis in children].

La Revue du praticien, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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