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Differential Diagnosis

The patient presents with a three-day history of diarrhea and left upper quadrant abdominal pain, which could be attributed to various causes. Here's a categorized differential diagnosis:

  • Single most likely diagnosis
    • Recurrent H. pylori infection: The patient's past medical history of H. pylori infection, positive antibody finger-prick test, and symptoms of diarrhea and abdominal pain make this a likely diagnosis. However, the urea breath test (UBT) will confirm whether the infection is active.
  • Other Likely diagnoses
    • Gastroesophageal reflux disease (GERD): The patient's symptoms of left upper quadrant abdominal pain and diarrhea could be related to GERD, especially given her history of cholecystectomy.
    • Irritable bowel syndrome (IBS): The patient's diarrhea and abdominal pain, in the absence of other alarming symptoms like blood in stool or fever, could suggest IBS.
    • Food poisoning or gastroenteritis: Although the patient denies recent travel or changes in diet, she does report biting her nails and kissing her dog, which could be potential sources of infection.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pancreatitis: The patient's left upper quadrant abdominal pain could be a sign of pancreatitis, which would require immediate medical attention.
    • Splenic infarction or rupture: Given the patient's location of pain, a splenic infarction or rupture should be considered, especially if she has a history of splenomegaly or other underlying conditions.
    • Gastric cancer: Although less likely, gastric cancer could present with similar symptoms, and the patient's past H. pylori infection increases her risk.
  • Rare diagnoses
    • Intestinal parasitism: The patient's symptoms of diarrhea and abdominal pain, combined with her habit of biting her nails and kissing her dog, could suggest an intestinal parasite infection, such as giardiasis.
    • Malabsorption syndrome: The patient's diarrhea and abdominal pain could be related to a malabsorption syndrome, such as celiac disease or lactose intolerance, although these would be less likely given her age and lack of other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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