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Last updated: August 5, 2025View editorial policy

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Differential Diagnosis for Swelling and Hardening of Left Forearm

  • Single Most Likely Diagnosis
    • Trauma or injury (e.g., fracture, bruise, or sprain): This is the most likely diagnosis due to the common occurrence of forearm injuries, which can cause swelling and hardening due to hematoma or callus formation.
  • Other Likely Diagnoses
    • Infection (e.g., cellulitis, abscess): Bacterial or fungal infections can cause swelling, redness, and hardening of the skin and underlying tissues in the forearm.
    • Inflammatory conditions (e.g., rheumatoid arthritis, gout): Chronic inflammatory conditions can cause swelling, pain, and stiffness in the forearm, potentially leading to hardening of the affected area.
    • Vascular conditions (e.g., deep vein thrombosis, vasculitis): Vascular issues can cause swelling, pain, and hardening of the forearm due to impaired blood flow or inflammation of blood vessels.
  • Do Not Miss Diagnoses
    • Compartment syndrome: A medical emergency characterized by increased pressure within a muscle compartment, leading to swelling, pain, and hardening of the affected area. If missed, it can result in permanent damage or necrosis.
    • Osteomyelitis: A bone infection that can cause swelling, pain, and hardening of the affected area, potentially leading to serious complications if left untreated.
    • Malignancy (e.g., soft tissue sarcoma): Although rare, malignancies can cause swelling and hardening of the forearm, emphasizing the importance of thorough evaluation and imaging studies.
  • Rare Diagnoses
    • Scleroderma: A chronic autoimmune disease that can cause hardening and thickening of the skin, potentially affecting the forearm.
    • Eosinophilic fasciitis: A rare condition characterized by inflammation and hardening of the fascia, a layer of tissue surrounding muscles, which can cause swelling and hardening of the forearm.
    • Necrotizing fasciitis: A rare but life-threatening infection that can cause swelling, pain, and hardening of the skin and underlying tissues, requiring prompt medical attention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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