Does teriparatide (Forteo) affect the kidneys?

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Last updated: March 6, 2025View editorial policy

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From the Research

Teriparatide (Forteo) does not have a direct, significant impact on kidney function, but its effects on the kidneys are not well-studied in the provided evidence. The provided studies do not directly address the effects of teriparatide on the kidneys. However, we can consider the general principles of medication effects on kidney function.

  • Medications that are primarily cleared through renal excretion may require dose adjustments in patients with kidney disease.
  • Medications that have a significant impact on blood pressure or fluid status may also affect kidney function.
  • Patients with existing kidney disease should be monitored closely when starting new medications, especially those that may affect kidney function.

The most recent and highest quality study provided is from 2023 1, but it does not address teriparatide or its effects on the kidneys.

  • This study discusses the prognostic implications of urinary potassium to creatinine ratio in patients with predialysis chronic kidney disease.
  • It highlights the importance of monitoring kidney function and electrolyte levels in patients with kidney disease.

Other studies provided discuss the effects of different medications on kidney function, such as levetiracetam 2, thiazide diuretics 3, 4, and telmisartan 5.

  • These studies suggest that certain medications may have beneficial or harmful effects on kidney function, depending on the specific medication and patient population.
  • However, they do not provide direct evidence about the effects of teriparatide on the kidneys.

In clinical practice, it is essential to monitor kidney function and electrolyte levels in patients with kidney disease who are starting new medications, including teriparatide.

  • Patients should be advised to maintain adequate hydration and report any changes in urine output or electrolyte levels.
  • Healthcare providers should be aware of the potential effects of medications on kidney function and adjust treatment plans accordingly.

References

Research

Prognostic Implications of Urinary Potassium to Creatinine Ratio in Patients With Predialysis Chronic Kidney Disease: A Cohort Study.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2023

Research

Thiazide Diuretics in Chronic Kidney Disease.

Current hypertension reports, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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