Cerebral Palsy: This condition is characterized by a group of permanent disorders appearing in early childhood, affecting movement, muscle tone, and posture. The presence of pseudobulbar palsy (indicative of upper motor neuron lesions affecting the brainstem) and significant speech delay, alongside global developmental delay, makes cerebral palsy a strong candidate, as it encompasses a range of neurological disorders that can lead to these symptoms.

Autism Spectrum Disorder (ASD): While primarily known for its effects on social interaction and communication, ASD can also present with developmental delays and, in some cases, may mimic or co-occur with conditions leading to pseudobulbar palsy. Speech delay is a common feature.
Rett Syndrome: A genetic disorder that almost exclusively affects girls, leading to severe impairments, affecting nearly every aspect of the child’s life: their ability to speak, walk, eat, and even breathe easily. It often presents with developmental regression, which could be mistaken for global developmental delay.
Angelman Syndrome: Characterized by developmental delays, speech impairment, and often ataxia, this condition could fit the described symptoms, especially considering the speech delay and potential for developmental issues.

Krabbe Disease: A rare, often fatal, lysosomal disorder that affects the nervous system. Its early symptoms can include developmental delay, and it can progress to more severe neurological deterioration, including pseudobulbar palsy. Early diagnosis is crucial for potential treatment options.
Metachromatic Leukodystrophy: Another lysosomal storage disease that affects the nerves, leading to developmental delays, and can cause pseudobulbar palsy among other symptoms. It's critical to diagnose early for possible interventions.
Adrenoleukodystrophy: A genetic disorder specified by a loss of the fatty covering (myelin) on nerve fibers within the brain. It can lead to developmental delays, speech problems, and eventually more severe neurological symptoms, including pseudobulbar palsy.

Pompe Disease: A genetic disorder caused by the deficiency of acid alpha-glucosidase, leading to glycogen accumulation in muscles. It can present with developmental delays and various degrees of muscle weakness, potentially affecting speech and leading to pseudobulbar symptoms in severe cases.
Mucopolysaccharidosis (MPS): A group of metabolic disorders caused by the absence or malfunctioning of enzymes needed to break down sugar molecules. Some types of MPS can lead to developmental delays, speech difficulties, and neurological problems, including pseudobulbar palsy.
Neuronal Ceroid Lipofuscinoses (NCL): A group of rare, inherited disorders that cause the progressive loss of mental and motor skills, with some forms presenting with developmental delays and speech impairment, potentially alongside pseudobulbar palsy symptoms.