Guidelines for Pediatric General Anesthesia Clearance
A comprehensive pre-anesthetic evaluation is essential for all pediatric patients undergoing general anesthesia, including assessment of medical history, physical examination with focused airway evaluation, appropriate fasting guidelines, and consideration of age-specific risk factors. 1
Pre-Anesthetic Health Evaluation
Medical History Assessment
- Age and weight (in kg) and gestational age at birth (preterm infants may have sequelae like apnea of prematurity)
- Health history including:
- Food and medication allergies and previous adverse drug reactions
- Complete medication history (prescription, over-the-counter, herbal)
- Relevant diseases and physical abnormalities
- Genetic syndromes that might increase airway obstruction risk
- Obesity, history of snoring or obstructive sleep apnea (OSA)
- Cervical spine instability (Down syndrome, Marfan syndrome, skeletal dysplasia)
- Pregnancy status in menarchal females (approximately 1% may be pregnant) 1
- History of prematurity
- Seizure disorders
- Previous hospitalizations
- Previous anesthesia experiences and complications
- Relevant family history (muscular dystrophy, malignant hyperthermia, pseudocholinesterase deficiency)
Physical Examination
- Vital signs: heart rate, blood pressure, respiratory rate, oxygen saturation, temperature
- Focused airway evaluation: tonsillar hypertrophy, abnormal anatomy (mandibular hypoplasia), Mallampati score
- ASA physical status classification 1
Special Considerations
- Sleep-disordered breathing/OSA: Children with severe OSA may require lower opioid doses (one-third to one-half of typical doses) due to altered mu receptors 1
- Herbal medicines: St. John's wort, ginkgo, ginger, ginseng, and garlic may alter drug pharmacokinetics through cytochrome P450 inhibition 1
- Drug interactions: Medications like erythromycin and cimetidine may inhibit cytochrome P450, prolonging sedation effects 1
Fasting Guidelines
Minimum Fasting Periods
- Clear liquids: 2 hours
- Human milk: 4 hours
- Infant formula: 6 hours
- Nonhuman milk: 6 hours
- Light meal: 6 hours 1
Fasting Considerations
- Recent guidelines from pediatric anesthesia societies are moving toward a 1-hour rule for clear fluids to reduce prolonged fasting 1
- Routine necessary medications may be taken with a sip of clear liquid on the day of procedure 1
- For emergency procedures, balance the risk of aspiration against the necessity of the procedure 1
Documentation Requirements
Pre-Procedure Documentation
- Informed consent according to local requirements
- Complete pre-anesthetic assessment
- ASA classification
- Fasting status
- Emergency contact information 1
During Procedure Documentation
- Time-based record of medications (name, route, site, time, dosage/kg)
- "Time out" confirmation of patient name, procedure, and site
- Monitoring data (consciousness level, vital signs, oxygen saturation, expired CO2) 1
Special Populations and Situations
Difficult Airway Management
- For children with difficult intubation, plan extubation when fully awake
- Consider extubation over a hollow airway exchange catheter when difficult extubation is anticipated
- Ensure full monitoring, trained assistance, and difficult airway equipment availability during extubation 1
Day Surgery Considerations
- Emergence delirium is more common in young children after short procedures
- Modify anesthetic techniques to minimize emergence delirium risk
- Provide clear instructions to parents about pain management at home
- Ensure parents understand appropriate dosage regimens for analgesics 1
Common Pitfalls and Caveats
- Inadequate fasting assessment: Always document and consider fasting status, especially for emergency procedures
- Overlooking OSA: Children with OSA require special consideration for opioid dosing
- Herbal medication interactions: Many herbal supplements can significantly alter anesthetic drug metabolism
- Inadequate parent preparation: Parents need clear instructions for managing post-anesthetic care, especially pain management
- Pregnancy status: Failure to assess pregnancy status in menarchal females (approximately 1% may be pregnant)
- Prolonged fasting: Unnecessarily prolonged fasting can lead to dehydration and hypoglycemia; follow updated guidelines allowing clear fluids up to 1-2 hours before procedures
By following these comprehensive guidelines for pediatric anesthesia clearance, clinicians can minimize risks and optimize outcomes for children undergoing general anesthesia.