What is the treatment approach for patients with other specific personality disorders?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment Approach for Other Specific Personality Disorders

The treatment of other specific personality disorders should primarily involve psychotherapy, with pharmacotherapy used as an adjunctive treatment for specific symptoms or comorbid conditions. While most evidence focuses on borderline personality disorder, the principles can be applied to other specific personality disorders with appropriate modifications.

Psychotherapeutic Approaches

First-Line Treatments

  1. Cognitive-Behavioral Therapy (CBT)

    • Demonstrated effectiveness in reducing suicidal ideation and behavior in patients with personality disorders 1
    • Typically involves fewer than 12 sessions
    • Helps patients identify and change problematic thinking and behavioral patterns
  2. Dialectical Behavior Therapy (DBT)

    • Particularly effective for patients with self-directed violence and emotional dysregulation 1
    • Combines elements of CBT, skills training, and mindfulness techniques
    • Focuses on developing skills in emotion regulation, interpersonal effectiveness, and distress tolerance
  3. Problem-Solving Therapy

    • Type of CBT aimed at improving ability to cope with stressful life experiences 1
    • Focuses on active problem solving
    • Particularly useful for patients with impaired coping mechanisms

Additional Psychotherapeutic Options

  • Psychoeducational Therapy

    • Provides information about the disorder, treatment options, and potential impact on functioning 1
    • Helps improve insight and treatment adherence
  • Family Therapy

    • Addresses family dynamics that may contribute to or be affected by the personality disorder 1
    • Enhances communication and problem-solving skills within the family system

Pharmacological Approaches

Medication should be used as an adjunctive treatment, targeting specific symptoms rather than the personality disorder itself:

  1. For anxiety symptoms

    • Selective Serotonin Reuptake Inhibitors (SSRIs) are preferred over benzodiazepines 1
    • Benzodiazepines should be used with caution due to potential for increased disinhibition or impulsivity 1
  2. For mood symptoms

    • Antidepressants (particularly SSRIs) for depressive symptoms 1
    • Mood stabilizers may be considered for mood lability
  3. For impulsivity or aggression

    • Low-dose antipsychotics may be considered for severe impulsivity or aggression
    • Careful monitoring for side effects is essential

Comprehensive Treatment Algorithm

  1. Initial Assessment

    • Evaluate specific personality traits and their impact on functioning
    • Screen for comorbid conditions (depression, anxiety, substance use disorders)
    • Assess suicide risk (particularly important as personality disorders have elevated suicide risk) 1
  2. Treatment Planning

    • Mild to moderate severity: Begin with individual psychotherapy (CBT or problem-solving therapy)
    • Moderate to severe with emotional dysregulation: Consider DBT
    • With family dysfunction: Add family therapy
    • With specific symptom clusters: Add targeted pharmacotherapy
  3. Ongoing Management

    • Regular follow-up to assess treatment response
    • Monitor for suicidal ideation
    • Adjust treatment approach based on response

Special Considerations

  • Comorbidity: Personality disorders frequently co-occur with other psychiatric conditions, which can complicate treatment 1, 2

  • Treatment Resistance: Patients with personality disorders often have poorer outcomes in treatment of comorbid conditions 3

  • Long-term Perspective: Treatment typically requires longer duration than for other psychiatric conditions 4

  • Access Issues: Despite evidence supporting specialized psychotherapies, these treatments are often unavailable in many healthcare systems 4

Common Pitfalls to Avoid

  • Underdiagnosis: Personality disorders are often undetected in clinical practice 2

  • Overreliance on Pharmacotherapy: Medications should target specific symptoms, not replace psychotherapy as the primary treatment 5

  • Inadequate Treatment Duration: Brief interventions may be insufficient; consider longer-term treatment planning 4

  • Countertransference Issues: Healthcare providers may experience negative reactions to patients with personality disorders, affecting treatment quality

The evidence base for treating personality disorders other than borderline personality disorder is limited, with small sample sizes and short follow-up periods in clinical trials 5. However, the available evidence suggests that psychotherapy should remain the cornerstone of treatment, with medications used as adjuncts for specific symptom management.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of personality disorder.

Lancet (London, England), 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.