Does Ozempic (semaglutide) cause allergic conjunctivitis?

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Last updated: March 6, 2025View editorial policy

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From the Research

Ozempic (semaglutide) may potentially cause allergic conjunctivitis, although it is not a commonly reported side effect, and patients should be monitored for any signs of allergic reactions. Allergic conjunctivitis is an inflammation of the eye's conjunctiva due to an allergic reaction, which can present as red, itchy, watery eyes. The exact relationship between Ozempic and allergic conjunctivitis is not well-established in the provided evidence, but any medication can trigger allergic reactions in susceptible individuals 1, 2.

Key Considerations

  • Allergic reactions occur when the immune system identifies a substance as harmful and produces antibodies against it, which can affect various body systems including the eyes.
  • If a patient develops eye symptoms after starting Ozempic, they should contact their healthcare provider promptly to evaluate whether the symptoms are related to Ozempic or have another cause.
  • Treatment for allergic conjunctivitis may include antihistamine eye drops, mast cell stabilizers, or nonsteroidal anti-inflammatory agents, with topical corticosteroids reserved for more severe cases under the guidance of an ophthalmologist 3, 4.

Management Approach

  • Patients experiencing symptoms of allergic conjunctivitis while on Ozempic should not discontinue the medication without medical advice.
  • Healthcare providers may need to consider medication adjustments or alternative treatments if the symptoms are deemed related to Ozempic.
  • The choice of treatment for allergic conjunctivitis should be guided by the severity of symptoms, the patient's medical history, and the potential for side effects, with a preference for treatments that improve patients' quality of life quickly and effectively 1, 2.

References

Research

[Seasonal and perennial allergic rhinoconjunctivitis].

Klinische Monatsblatter fur Augenheilkunde, 2014

Research

[Seasonal and Perennial Allergic Rhinoconjunctivitis].

Laryngo- rhino- otologie, 2017

Research

Allergic conjunctivitis.

Immunology and allergy clinics of North America, 2008

Research

The current and future therapy of allergic conjunctivitis.

Current opinion in ophthalmology, 1998

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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