What are the musculocutaneous nerve and brachial vessels?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 11, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Musculocutaneous Nerve and Brachial Vessels

The musculocutaneous nerve arises from the lateral cord of the brachial plexus (C5-T1) and innervates the brachial flexor muscles (coracobrachialis, biceps brachii, and brachialis), while the brachial vessels consist of the brachial artery and accompanying veins that run through the medial aspect of the arm.

Musculocutaneous Nerve

Anatomy and Course

  • Originates from the lateral cord of the brachial plexus (C5-T1)
  • Typically pierces the coracobrachialis muscle approximately 5-8 cm distal to the coracoid process 1
  • Runs between the biceps and brachialis muscles
  • Provides motor innervation to three muscles:
    • Coracobrachialis
    • Biceps brachii
    • Brachialis
  • Continues distally as the lateral antebrachial cutaneous nerve, providing sensory innervation to the lateral forearm 1, 2

Anatomical Variations

  • Communicating branches with the median nerve are common and can be classified into five types 1
  • Complete absence of the musculocutaneous nerve occurs in 1.4-15% of cases, with its functions taken over by the median nerve 3, 4
  • Variations in motor branches to biceps brachii:
    • Type I (most common): A common primary branch that bifurcates to supply both heads
    • Type II: Two separate primary branches from the main trunk
    • Type III: Similar to type I but with an additional distal motor branch 2

Brachial Vessels

Brachial Artery

  • Main arterial supply to the arm
  • Continuation of the axillary artery at the lower border of the teres major muscle
  • Runs medially in the arm within the medial neurovascular bundle
  • Located medial to the humerus in the proximal arm and anterior to it distally
  • Terminates at the cubital fossa by dividing into the radial and ulnar arteries 5

Major Branches

  • Profunda brachii artery (deep brachial artery)
  • Superior and inferior ulnar collateral arteries
  • Nutrient artery to the humerus 5

Brachial Veins

  • Paired vessels that accompany the brachial artery
  • Receive tributaries corresponding to the branches of the brachial artery
  • Unite with the basilic vein to form the axillary vein 5

Clinical Significance

Surgical Access

  • A 2×2 inch "key window" on the medial surface of the arm, centered 2 inches distal to the axillary fold, provides access to major neurovascular structures including:
    • Median, ulnar, and musculocutaneous nerves
    • Brachial artery and veins
    • Basilic vein
    • Profunda brachii artery 5

Vascular Access

  • The brachial artery is commonly used for:
    • Blood pressure measurement
    • Arterial blood sampling
    • Flow-mediated dilation studies 6
  • Ultrasound imaging of the brachial artery is typically performed above the antecubital fossa in the longitudinal plane 6

Nerve Injury Implications

  • Injury to the musculocutaneous nerve results in:
    • Weakness in elbow flexion
    • Sensory loss on the lateral forearm
  • In cases of anatomical variation where the median nerve supplies the brachial flexors, injury to the median nerve would cause unexpected paralysis of elbow flexion 4

Imaging Considerations

  • For ultrasound assessment of the brachial artery, longitudinal images are preferred over cross-sectional images for accurate diameter measurement 6
  • Clear visualization of both near (anterior) and far (posterior) wall lumen-intima boundaries indicates proper imaging plane 6

Understanding these anatomical structures and their variations is crucial for surgical approaches to the arm, nerve repair procedures, vascular access, and accurate interpretation of clinical findings in upper limb pathologies.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.