Malar Edema: Swelling Under the Eyes After Filler Injections
Swelling under the eyes after filler injections is most commonly referred to as "malar edema," which is a recognized complication of periorbital filler treatments.
Causes of Malar Edema
Malar edema following filler injections can occur due to several mechanisms:
Veno-lymphatic compression:
- Recent evidence suggests that filler deposits can compress the venous and lymphatic drainage in the periocular region 1
- Ultrasound studies have shown that in 23 of 26 affected eyes, filler material was located inside the SMAS (superficial musculoaponeurotic system), potentially disrupting normal fluid drainage 1
Filler placement issues:
- Improper placement of filler material, particularly when injected too superficially or in excessive amounts
- Filler placement on the periosteum of the orbital rim has been associated with malar edema in some cases 1
Timing of onset:
- Can present as either early-onset (within days of injection) or late-onset (weeks to years after treatment)
- Studies show approximately 76% of cases have early onset, while 24% show late onset 1
Clinical Characteristics
Malar edema presents with:
- Soft tissue swelling under the eyes
- May be unilateral or bilateral
- Can persist for extended periods (chronic cases)
- Occurs in approximately 11% of patients receiving periocular fillers 2
Management Options
Hyaluronidase treatment (for hyaluronic acid fillers):
- The most effective treatment for malar edema caused by HA fillers
- Local infiltration of approximately 0.2-0.5 ml of hyaluronidase (20-75 IU) per eyelid 3
- Ultrasound-guided filler removal has shown immediate clinical improvement in malar edema cases 1
- After hyaluronidase treatment, restored venous flow can be observed in the superficial and/or deep fatty layers 1
For permanent fillers (e.g., Bio-Alcamid):
- More challenging to manage
- Attempted removal by aspiration or bimanual expression may result in further migration of the product 4
- Surgical excision may be necessary in some cases
Prevention Strategies
To minimize the risk of malar edema:
- Use appropriate injection techniques and placement
- Avoid overfilling the periocular area
- Consider the patient's anatomical features and predisposition to edema
- Use hyaluronic acid fillers rather than permanent fillers in the periocular region
- Understand the periorbital anatomy, including the location of glands, nerves, and vasculature 5
Important Considerations
- Malar edema is a unique complication specific to the periocular area 2
- While most adverse events are mild and self-resolve within 1 month, chronic cases can persist for years 2, 5
- Patients with a history of malar edema should be cautioned about receiving additional filler treatments in the periocular region
- Proper anatomical knowledge is crucial when performing periocular filler injections to avoid complications 5
Pitfalls to Avoid
- Do not attempt to remove permanent fillers through aspiration or expression, as this may cause migration and abscess formation 4
- Avoid excessive filler placement in the periocular region
- Be aware that malar edema can occur even years after initial filler placement 5, 4
- Don't confuse malar edema with other causes of periorbital swelling such as allergic reactions or infections