From the Research
Management Approach for Osteoarthritis with Impaired Renal Function
The management of osteoarthritis (OA) in patients with impaired renal function requires careful consideration of the potential risks and benefits of various treatment options.
- The use of nonsteroidal anti-inflammatory drugs (NSAIDs) may be limited in patients with impaired renal function due to the potential for worsening renal function 1, 2.
- Acetaminophen may be a safer alternative for pain management in patients with OA and impaired renal function 1, 3.
- Intra-articular injections of hyaluronic acid-like products or corticosteroids may be considered for short-term pain relief 1, 2.
- Nonpharmacologic measures such as patient education, weight loss, and exercise are also important components of OA management and may be particularly beneficial for patients with impaired renal function 1, 2, 3.
- Renal insufficiency has been identified as a significant association factor for severe knee pain in patients with OA, highlighting the need for careful management of pain in patients with impaired renal function 4.
Considerations for Patients with Impaired Renal Function
- Patients with impaired renal function may require closer monitoring and adjustment of their treatment plan to minimize the risk of adverse effects 4, 2.
- The use of topical agents, viscosupplementation, and surgery may be considered in individualized treatment plans for patients with OA and impaired renal function 3, 5.
- A comprehensive approach to OA management that incorporates nonpharmacologic and pharmacologic therapies, as well as consideration of the patient's renal function, is essential for optimizing outcomes in patients with OA and impaired renal function 1, 2, 3, 5.