What is the relationship between hypertension and energy?

From the Guidelines

Hypertension is directly related to energy expenditure and balance, with prolonged exposure to sedentary lifestyles and excessive calorie consumption leading to increased blood pressure, particularly systolic blood pressure, as noted in the study by 1. The relationship between hypertension and energy is complex, involving various factors such as lifestyle, diet, and physical activity. Key points to consider include:

• Maintaining a healthy body weight, as weight is positively associated with blood pressure and hypertension, with reductions in blood pressure occurring before attainment of desirable body weight, as indicated by studies 1 and 1.
• Engaging in regular physical activity, such as 30 minutes of moderate exercise daily, to manage energy and improve cardiovascular function, as recommended by the 2020 International Society of Hypertension global hypertension practice guidelines 1.
• Limiting caffeine, alcohol, and high-sodium foods, which can exacerbate hypertension and associated energy surges.
• Reducing stress and inducing mindfulness through practices like transcendental meditation or mindfulness, which have been shown to lower blood pressure, as suggested by 1.
• Implementing lifestyle modifications, including salt reduction, a healthy diet, moderation of alcohol consumption, weight reduction, smoking cessation, and regular physical activity, as outlined in the 2020 International Society of Hypertension global hypertension practice guidelines 1.

The most effective approach to managing the relationship between hypertension and energy is to focus on lifestyle modifications, particularly maintaining a healthy body weight, engaging in regular physical activity, and reducing stress, as these have been shown to have a significant impact on blood pressure and overall cardiovascular health, as noted in the study by 1.

From the FDA Drug Label

The FDA drug label does not answer the question.

From the Research

Relationship Between Hypertension and Energy

• Hypertension is a major risk factor for various cardiovascular diseases, including heart attack, stroke, and kidney disease 2.
• The development of high blood pressure is associated with changes in carbohydrate and lipid metabolism, as well as organ damage, mainly to the heart and kidneys 3.
• Lifestyle modifications, such as weight loss, healthy dietary patterns, physical activity, and limited alcohol consumption, are recommended as first-line therapy for hypertension 4.
• Exercise training, including high-intensity interval training (HIIT), has been shown to reduce blood pressure in hypertensive subjects 5.
• Psychosocial stress is known to contribute to the development and worsening of hypertension, and careful follow-up is necessary for patients with stress-related blood pressure responses 6.

Mechanisms Involved in Hypertension

• The renin-angiotensin system (RAS) plays a crucial role in blood pressure control and is involved in the metabolism of glucose, homeostasis, and balance of electrolytes in the body 2.
• Angiotensin-converting enzyme (ACE) is a key component of RAS and is involved in the conversion of angiotensin I to angiotensin II, as well as the degradation of bradykinin 2.
• Calcium channel antagonists and ACE inhibitors have synergistic effects on sodium and fluid balance and on the renin-angiotensin-aldosterone system, making them a potential combination therapy for hypertension 3.

Treatment and Management of Hypertension

• First-line drug therapy for hypertension consists of thiazide or thiazide-like diuretics, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, and calcium channel blockers 4.
• The decision to initiate antihypertensive medication should be based on the level of blood pressure and the presence of high atherosclerotic cardiovascular disease risk 4.
• Lifestyle modifications and exercise training can be effective in reducing blood pressure and improving overall health in hypertensive patients 4, 5.