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Last updated: August 12, 2025View editorial policy

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Differential Diagnosis for Facial Rash

  • Single most likely diagnosis
    • Eczema (Atopic Dermatitis): This is a common condition characterized by itchy, inflamed skin, which can appear as a rash on the face. It's often seen in individuals with a history of allergies or asthma.
  • Other Likely diagnoses
    • Acne: A skin condition that occurs when your hair follicles become plugged with oil and dead skin cells, leading to pimples and sometimes a rash-like appearance on the face.
    • Contact Dermatitis: A type of inflammation of the skin that occurs when the skin comes into contact with an irritant or allergen, leading to a rash.
    • Rosacea: A condition characterized by a red rash on the face, often accompanied by acne-like symptoms, and can be triggered by various factors including sun exposure, stress, and certain foods.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Lupus: A chronic autoimmune disease that can cause a butterfly-shaped rash across the cheeks and nose, among other symptoms. Early diagnosis is crucial for effective management.
    • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth of the skin, which can appear as a rash. It requires prompt antibiotic treatment to prevent serious complications.
    • Meningitis (in cases of petechial rash): Although rare, a petechial rash (small red or purple spots) on the face can be a sign of meningitis, especially in children. This is a medical emergency.
  • Rare diagnoses
    • Sarcoidosis: A disease characterized by the growth of tiny collections of inflammatory cells (granulomas) in any part of the body, which can cause a rash on the face, among other symptoms.
    • Dermatomyositis: An inflammatory disease characterized by muscle weakness and a distinctive skin rash, which can appear on the face.
    • Kawasaki Disease: A rare condition mainly affecting children under the age of 5, characterized by a fever, rash, and swelling of the hands and feet, which can sometimes involve the face.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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