Treatment of Nasal Polyps in Children
The first-line treatment for children with nasal polyps is intranasal corticosteroids, with oral corticosteroids reserved for severe cases, and surgery considered when medical management fails. 1
Evaluation and Diagnosis
When evaluating a child with nasal polyps, several important considerations should guide your approach:
- Underlying conditions: Nasal polyps in children should prompt evaluation for cystic fibrosis, as they occur in up to 50% of children with this condition 1, 2
- Clinical presentation: Children typically present with nasal obstruction, congestion, and potential loss of smell rather than facial pain or headache 2
- Physical examination: Nasal polyps appear as pale gray, semitranslucent growths in contrast to the surrounding pink nasal mucosa 2
Treatment Algorithm
First-Line Treatment
- Intranasal corticosteroids
- Mainstay of treatment for nasal polyps in children 1, 3
- Significantly reduces polyp size, nasal congestion, and rhinorrhea 2
- For children 4-11 years: Fluticasone propionate nasal spray 1 spray in each nostril once daily 4
- Duration: Should use for shortest time necessary to achieve symptom relief; consult doctor if needed beyond 2 months 4
Second-Line Treatment
- Short course of oral corticosteroids
Adjunctive Treatments
Saline nasal irrigation
- Helps with mechanical clearance of mucus and inflammatory products 5
- Improves effectiveness of intranasal corticosteroids
Antibiotics
Surgical Management
- Surgical intervention
- Indicated when medical management fails to control symptoms 1
- Consider when polyps cause severe obstruction or recurrent sinusitis 2
- In children with antral choanal polyps, combined Caldwell-Luc antrostomy and polypectomy may be most successful 6
- Functional endoscopic sinus surgery (FESS) is the preferred surgical approach for most cases 7
Special Considerations
Cystic Fibrosis
- Children with nasal polyps should be evaluated for cystic fibrosis 2, 6
- In patients with cystic fibrosis, 60% can be adequately managed with intranasal polypectomy alone 6
- The inflammatory profile differs from non-CF polyps, with increased neutrophils rather than eosinophils 1
Allergic Fungal Rhinosinusitis
- Consider this diagnosis in children with nasal polyps and evidence of fungal involvement 1
- May require more aggressive treatment and antifungal consideration
Monitoring and Follow-up
- Monitor growth in children using intranasal corticosteroids, as they may affect growth rate in some children 4
- Regular follow-up is essential to assess treatment response and adjust therapy as needed
- Recurrence is common, requiring ongoing maintenance therapy with intranasal corticosteroids 8, 3
Pitfalls and Caveats
Growth concerns: Long-term use of intranasal corticosteroids may affect growth velocity in some children; use for shortest duration necessary 4
Misdiagnosis: Unilateral nasal masses in children should be carefully evaluated to rule out other conditions beyond inflammatory polyps 6
Incomplete treatment: Focusing only on polyp removal without addressing underlying inflammation leads to high recurrence rates 3
Delayed diagnosis of cystic fibrosis: Always consider and test for cystic fibrosis in children with nasal polyps 1, 2
Overuse of antibiotics: Antibiotics should only be used when there is clear evidence of infection, not as routine management 3
Remember that nasal polyps in children are unlikely to be completely cured by either medical or surgical therapy alone, but symptoms can generally be controlled with appropriate management 7.