How to manage a patient with hyperglycemia before discharge?

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Last updated: August 13, 2025View editorial policy

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Managing a Patient with Blood Glucose of 350 Before Discharge

For a patient with a blood glucose of 350 mg/dL before discharge, implement a structured discharge plan including medication adjustment, education on diabetes self-management, and scheduling a follow-up appointment within 1-2 weeks to prevent complications and hospital readmission. 1

Immediate Pre-Discharge Assessment

  1. Evaluate the cause of hyperglycemia:

    • Review inpatient glucose trends
    • Check HbA1c if not already done (indicates pre-admission control)
    • Determine if this is new-onset diabetes, poorly controlled known diabetes, or stress hyperglycemia
  2. Medication management based on HbA1c:

    • HbA1c < 7.5-8%: Resume prehospitalization treatment regimen with possible adjustments 1
    • HbA1c 8-9%: Consider adding or adjusting basal insulin (50% of hospital basal dose) 1
    • HbA1c > 9%: Continue basal-bolus insulin regimen or seek diabetes specialist consultation 1

Discharge Medication Protocol

For patients with Type 1 Diabetes:

  • Resume previous basal-bolus insulin regimen but adjust doses based on inpatient requirements 1
  • Never discontinue basal insulin

For patients with Type 2 Diabetes:

  • Previously on oral agents only:

    • If HbA1c < 8%: Resume previous medications if no contraindications
    • If HbA1c 8-9%: Resume oral agents plus add basal insulin at 50% of hospital dose 1
    • If HbA1c > 9% or glucose consistently >250 mg/dL: Consider basal-bolus insulin regimen 1
  • Previously on insulin:

    • Continue insulin regimen with adjustments based on inpatient requirements
    • If transitioning from IV to subcutaneous insulin, give basal insulin 2 hours before stopping IV infusion 1

For stress hyperglycemia (no previous diabetes):

  • Consider short-term follow-up without medications if clinical judgment suggests transient hyperglycemia

Essential Patient Education Before Discharge

Provide clear instructions on:

  1. Blood glucose monitoring:

    • Target glucose ranges
    • Frequency of monitoring
    • When to call healthcare provider (e.g., persistent readings >300 mg/dL)
  2. Medication management:

    • Proper insulin administration technique if applicable
    • Timing of medications
    • Dose adjustments if prescribed
  3. Hypoglycemia recognition and treatment:

    • Symptoms (shakiness, confusion, sweating)
    • Treatment (15-15 rule: 15g carbohydrate, recheck in 15 minutes)
  4. Sick day management 1

  5. Nutrition guidance:

    • Consistent carbohydrate intake
    • Meal planning
    • Consider referral to registered dietitian

Follow-up Planning

  • Schedule follow-up appointment before discharge to increase attendance likelihood 1
  • For patients with hyperglycemia during hospitalization, schedule follow-up within 1-2 weeks 1
  • For poorly controlled diabetes (HbA1c >9%), consider expedited endocrinology referral 1

Medication Reconciliation

  • Cross-check home and hospital medications to ensure safety 1
  • Provide clear written instructions on which medications to continue, discontinue, or adjust
  • Ensure patient has access to prescribed medications before discharge

Special Considerations

  • For elderly patients (≥80 years), consider less stringent glycemic targets (HbA1c <8%) to minimize hypoglycemia risk 2
  • For patients with nephropathy or other complications, target HbA1c of 7-8% to balance glycemic control with hypoglycemia risk 2
  • Avoid discharge with sliding scale insulin alone as the sole regimen 1

Documentation and Communication

  • Transmit discharge summary to primary care provider as soon as possible 1
  • Include clear information about:
    • Cause of hyperglycemia
    • Treatment changes made during hospitalization
    • Follow-up plan
    • Medication adjustments

By following this structured approach, you can effectively manage patients with hyperglycemia before discharge, reducing the risk of complications and readmission while ensuring continuity of care.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Type 2 Diabetes Mellitus with Nephropathy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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