Treatment of Acute Bronchitis
Antibiotics are not recommended for routine treatment of acute bronchitis in immunocompetent adults, as it is primarily a viral illness that resolves without antibiotic therapy. 1
Diagnosis and Differentiation
Acute bronchitis is characterized by an acute cough with or without phlegm production lasting up to 3 weeks with a normal chest radiograph. Before establishing this diagnosis, it's essential to exclude:
- Pneumonia
- Common cold
- Acute asthma
- Exacerbation of COPD 1
Pneumonia should be ruled out if any of the following are present:
- Heart rate >100 beats/min
- Respiratory rate >24 breaths/min
- Oral temperature >38°C
- Focal chest examination findings 2, 1
Treatment Approach
First-Line Management
Patient Education:
Symptomatic Relief:
Environmental Modifications:
- Eliminate environmental cough triggers (dust, dander)
- Avoid respiratory irritants including smoke exposure 1
What NOT to Use Routinely
- Antibiotics: Not indicated for routine treatment as they provide minimal benefit (reducing cough by only about half a day) while exposing patients to risks of adverse effects 2, 1, 3
- Beta-agonist bronchodilators: Not recommended for most patients with acute bronchitis (Grade D recommendation) 2
- Mucokinetic agents: Not recommended due to no consistent favorable effect on cough (Grade I recommendation) 2
- Inhaled corticosteroids: No evidence supporting routine use 1
- Oral corticosteroids: Not recommended for routine use 1
- NSAIDs: Not recommended specifically for bronchitis treatment 1
Special Considerations
When to Consider Antibiotics
Antibiotics should only be considered in specific situations:
- Pertussis (whooping cough): Macrolide antibiotics (e.g., erythromycin) are indicated for confirmed or suspected pertussis to reduce transmission (Grade A recommendation) 2
- Patients at high risk for pneumonia: Particularly those ≥65 years old 4
- Worsening bronchitis with suspected bacterial superinfection 1
Bronchodilator Consideration
In select adult patients with wheezing accompanying the cough, treatment with β-agonist bronchodilators may be useful (Grade C recommendation) 2
Common Pitfalls in Management
Overuse of antibiotics: Despite guidelines, 65-80% of patients with acute bronchitis receive antibiotics unnecessarily 2, 1
Failure to distinguish between acute bronchitis and pneumonia: Careful assessment of vital signs and physical examination findings is essential 1
Unrealistic expectations: Not informing patients about the typical duration of cough (2-3 weeks) often leads to unnecessary follow-up visits and antibiotic prescriptions 1, 3
Inappropriate use of mucokinetic agents/expectorants: These have not shown consistent favorable effects 2, 1
Recurrent Episodes
For patients with recurrent bronchitis episodes, consider:
- Cough variant asthma (found in 65% of patients with recurrent bronchitis)
- Bronchiectasis
- Chronic bronchitis (productive cough for ≥3 months in 2 consecutive years)
- Non-asthmatic eosinophilic bronchitis 1
By following these evidence-based recommendations, clinicians can provide appropriate care for patients with acute bronchitis while avoiding unnecessary antibiotic use and its associated risks.