What are the implications of a prominent column of Bertin (renal column)

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Implications of Prominent Column of Bertin

A prominent column of Bertin (also called junctional parenchyma) is a normal anatomical variant that requires no specific intervention or follow-up unless it is causing diagnostic confusion with a renal mass.

Definition and Characteristics

A column of Bertin is normal renal cortical tissue that extends into the renal sinus between renal pyramids. When prominent, it can mimic a renal mass on imaging, particularly on ultrasound, creating a diagnostic dilemma 1.

Key characteristics of a prominent column of Bertin include:

  • Located between overlapping portions of two renal sinus systems 2
  • Continuous with the adjacent renal cortex 2, 3
  • Echogenicity similar to that of normal renal cortex 4, 3
  • Typically indents the renal sinus laterally 4
  • Usually less than 3 cm in largest dimension 4
  • Contains normal renal cortex, pyramids, and columns (septa) of Bertin 2
  • Smooth renal contour 3

Clinical Significance

The primary clinical significance of a prominent column of Bertin is its potential to be misinterpreted as a renal mass, which may lead to:

  1. Unnecessary diagnostic procedures (biopsies)
  2. Unnecessary surgical interventions, including nephrectomy 1
  3. Patient anxiety and healthcare costs associated with follow-up imaging

Diagnostic Approach

When a prominent column of Bertin is suspected:

  1. Ultrasound with Doppler studies is often sufficient for diagnosis 1, 5

    • Assess continuity with renal cortex
    • Evaluate echogenicity compared to normal cortex
    • Confirm normal blood flow pattern
  2. MRI is particularly useful for definitive diagnosis in ambiguous cases 1

    • Shows identical signal intensity to normal renal cortex on all sequences
    • Demonstrates normal enhancement pattern following contrast administration
  3. CT with contrast can also be diagnostic 1

    • Shows enhancement pattern identical to normal renal cortex
  4. Nuclear medicine studies may show decreased isotope uptake compared to normal renal tissue 6, but this is not typically necessary for diagnosis

Management Recommendations

  1. No intervention is required for a confirmed prominent column of Bertin, as it represents normal renal tissue

  2. No specific follow-up imaging is needed once the diagnosis is confirmed 5

  3. Documentation in the patient's medical record is important to prevent future diagnostic confusion

  4. Patient reassurance that this is a normal anatomical variant with no clinical significance

Potential Pitfalls

  • Misdiagnosis as a renal mass, particularly renal cell carcinoma
  • Unnecessary biopsy or surgical intervention
  • Failure to recognize the characteristic imaging features
  • Over-reliance on a single imaging modality when findings are equivocal

Conclusion

A prominent column of Bertin is a normal anatomical variant that has no pathological significance. The primary importance lies in accurate identification to avoid unnecessary procedures and patient anxiety. When typical imaging features are present, no further evaluation or follow-up is required.

References

Research

Hypertrophic columns of bertin: imaging findings.

The Eurasian journal of medicine, 2014

Research

Sonography of the hypertrophied column of Bertin.

AJR. American journal of roentgenology, 1986

Research

The sonography of renal columnar hypertrophy.

Journal of clinical ultrasound : JCU, 1983

Guideline

Renal Ultrasound Evaluation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Pseudotumor of kidney.

Urology, 1979

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.