What is the recommended treatment for a patient diagnosed with musculoskeletal strain?

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Treatment for Musculoskeletal Strain

Topical NSAIDs with or without menthol gel should be used as first-line therapy for musculoskeletal strain to reduce pain, improve function, and enhance treatment satisfaction. 1

First-Line Treatment Approach

Topical Treatments

  • Apply topical NSAIDs to the affected area of the right-sided back and hip 3-4 times daily 1, 2
  • Consider adding menthol gel (such as Biofreeze) for additional pain relief 1, 2
  • Topical treatments minimize systemic exposure while providing localized pain relief 2

Rest and Activity Modification

  • Implement relative rest for the affected area while maintaining activity in unaffected areas
  • Avoid activities that exacerbate pain, particularly heavy lifting which triggered the injury 3
  • Gradually return to normal activities as pain subsides

Physical Interventions

  • Apply ice to the affected area for 15-20 minutes every 2-3 hours during the first 24-48 hours to reduce inflammation 3
  • Use compression (such as an elastic bandage) to provide support and reduce swelling 3
  • Consider appropriate bracing if the strain affects joint stability 2

Second-Line Treatment Options

If first-line treatment is insufficient after 3-5 days:

Oral Medications

  • Oral NSAIDs: Consider naproxen or other non-selective NSAIDs if topical treatments are inadequate 1

    • Use the lowest effective dose for the shortest possible duration 2
    • Monitor for gastrointestinal side effects
  • Acetaminophen: Alternative option if NSAIDs are contraindicated or poorly tolerated 1

    • Use up to 3,000 mg/day in divided doses 2
  • Muscle Relaxants: Consider cyclobenzaprine for short-term use (up to 2-3 weeks) if muscle spasm is prominent 4

    • Be aware of potential side effects including drowsiness and dry mouth 4

Non-Pharmacological Interventions

  • Physical Therapy: Initiate as pain and swelling subside 3

    • Focus on restoring flexibility and strength to the affected muscles 2
    • Include core strengthening exercises to support the back 2
  • Transcutaneous Electrical Nerve Stimulation (TENS): May help reduce pain in some patients 1

  • Acupressure: Consider for pain reduction and improved physical function 1

Important Considerations and Cautions

Avoid Opioids

  • Opioids (including tramadol) should be avoided for treatment of musculoskeletal strain 1
  • The risks of opioid use outweigh potential benefits for this condition

Duration of Treatment

  • NSAIDs should be used for the shortest possible time to minimize adverse effects 1
  • Muscle relaxants should only be used for short periods (2-3 weeks maximum) 4

Special Populations

  • In patients with cardiovascular disease, use a stepped care approach starting with acetaminophen or non-acetylated salicylates before considering NSAIDs 1
  • For patients with gastrointestinal risk factors, consider adding a proton pump inhibitor if oral NSAIDs are necessary 2

Follow-up and Progression

  • Evaluate response to initial treatment after 4-7 days 2
  • If symptoms persist beyond 2-3 weeks despite appropriate treatment, reassess the diagnosis and consider additional imaging or specialist referral 3
  • Gradually increase activity as symptoms improve, with focus on preventing recurrence through proper body mechanics and strengthening exercises 2

Prevention of Recurrence

  • Implement proper warm-up before physical activity, especially before heavy lifting 3
  • Strengthen core and back muscles to provide better support during activities 2
  • Improve workplace ergonomics to reduce strain during lifting and other activities 1
  • Maintain flexibility through regular stretching 3

The evidence strongly supports a conservative approach focusing on topical anti-inflammatory medications first, followed by oral medications only if needed, while incorporating appropriate physical therapy and activity modification to promote healing and prevent recurrence.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Osteoarthritis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Muscle strain injury: diagnosis and treatment.

The Journal of the American Academy of Orthopaedic Surgeons, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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