What is the recommended treatment for contact dermatitis?

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Last updated: August 14, 2025View editorial policy

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Treatment of Contact Dermatitis

The recommended first-line treatment for contact dermatitis includes topical corticosteroids, soap substitutes, and emollients, with allergen identification and avoidance as essential components of management. 1

Initial Management Algorithm

Step 1: Identify and Avoid Triggers

  • Determine whether irritant or allergic contact dermatitis
  • For allergic contact dermatitis: identify and completely avoid allergen exposure 2
  • For irritant contact dermatitis: minimize exposure to irritants (soaps, detergents, water) 1
  • Consider workplace assessment for occupational cases 1

Step 2: Acute Treatment

  1. Mild cases:

    • Over-the-counter hydrocortisone 1% cream 3-4 times daily 3
    • Apply to affected areas for up to 7 days
  2. Moderate cases:

    • Mid to high-potency topical corticosteroids (e.g., triamcinolone 0.1%, betamethasone dipropionate) 2, 4
    • Apply thinly twice daily for 5-7 days
  3. Severe cases (>30% body surface area or severely limiting daily activities):

    • Oral prednisone 0.5-1 mg/kg/day for 1-2 weeks with 4-6 week taper 2, 5
    • Important: Rapid discontinuation may cause rebound dermatitis 4, 5
    • Consider proton pump inhibitor for GI prophylaxis during systemic steroid use 2

Step 3: Skin Barrier Repair

  • Use soap substitutes for washing 1
  • Apply fragrance-free, dye-free moisturizers in tubes (not jars) 2
  • "Soak and smear" technique for hands: soak in plain water for 20 minutes then immediately apply moisturizer to damp skin nightly for up to 2 weeks 2

Special Considerations

For Chronic or Recurrent Cases

  • Consider patch testing if persistent or recurrent 1, 4
  • Second-line treatments for steroid-resistant cases:
    • Topical calcineurin inhibitors (tacrolimus) 1, 2
    • For chronic hand dermatitis: psoralen plus UVA, azathioprine, or ciclosporin 1

For Children

  • Use lower potency corticosteroids in children due to increased risk of side effects 6
  • Avoid potent agents in pediatric patients 6
  • For children under 2 years: consult a doctor before using hydrocortisone 3

For Occupational Cases

  • After-work creams provide protection against developing irritant contact dermatitis 1
  • Make moisturizers readily available in the workplace 1
  • Note: Barrier creams alone have questionable value in protecting against irritants 1

Prevention Strategies

  • Apply moisturizer after washing hands and before wearing gloves 2
  • Use gentle skin care practices and avoid known irritants 2
  • For healthcare workers (high-risk group): minimize exposure to harsh chemicals and frequent hand washing 2

When to Refer to a Specialist

  • Failure to respond to appropriate first-line treatment
  • Recurrent episodes despite preventive measures
  • Suspicion of allergic contact dermatitis requiring patch testing
  • Uncertainty about diagnosis 2

Prognosis

The prognosis for contact dermatitis depends on allergen avoidance. For milder cases with successful avoidance, dermatitis will clear. However, occupational contact dermatitis often has a poor long-term prognosis, with studies showing only 25% of patients completely healed after 10 years 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Allergic Contact Dermatitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Diagnosis and management of contact dermatitis.

American family physician, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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