Differential Diagnosis for Neuroopathy on Bottom of Foot with Burning Sensation

• Single Most Likely Diagnosis
  • Diabetic Neuropathy: This is the most likely diagnosis due to the high prevalence of diabetes and its well-known complication of peripheral neuropathy, which can cause burning sensations in the feet.
• Other Likely Diagnoses
  • Peripheral Artery Disease (PAD): Reduced blood flow to the feet can cause pain, burning, and numbness, making PAD a plausible diagnosis.
  • Tarsal Tunnel Syndrome: Compression of the posterior tibial nerve can cause burning sensations, numbness, and pain on the bottom of the foot.
  • Morton's Neuroma: A benign growth that can cause burning pain, usually between the toes, but can also affect the bottom of the foot.
• Do Not Miss Diagnoses
  • Deep Vein Thrombosis (DVT): Although less common, DVT can cause severe pain and burning sensation in the foot and leg, and missing this diagnosis can be life-threatening.
  • Infection (e.g., Cellulitis or Abscess): Infections can cause severe pain, burning, and redness, and prompt treatment is necessary to prevent serious complications.
  • Charcot Foot: A complication of diabetes that can cause severe pain, burning, and deformity of the foot, which can lead to serious consequences if left untreated.
• Rare Diagnoses
  • Leprosy (Hansen's Disease): A rare infectious disease that can cause nerve damage, leading to burning sensations and numbness in the feet.
  • Sjögren's Syndrome: An autoimmune disorder that can cause peripheral neuropathy, leading to burning sensations in the feet.
  • Amyloidosis: A rare condition that can cause peripheral neuropathy, leading to burning sensations and numbness in the feet.