From the Research
Chasteberry and N-acetylcysteine (NAC) may be considered as adjunctive treatments for ovarian cysts, particularly in women with polycystic ovary syndrome (PCOS), but the evidence is limited and they should not replace conventional medical treatment. When considering the use of Chasteberry and NAC for ovarian cysts, it is essential to weigh the potential benefits and risks. Chasteberry (Vitex agnus-castus) may help balance hormones by affecting prolactin levels, potentially benefiting women with PCOS, as suggested by a systematic review of clinical trials 1. A typical dose is 20-40 mg daily of standardized extract. NAC, an antioxidant supplement, has shown promise in some studies for reducing cyst size and improving insulin sensitivity in women with PCOS at doses of 600 mg three times daily for 3-6 months, as reported in an observational cohort study 2. However, neither supplement is FDA-approved for treating ovarian cysts, and they shouldn't replace conventional medical treatment.
Some key points to consider when using Chasteberry and NAC for ovarian cysts include:
- The evidence for their effectiveness is limited, and more research is needed to fully understand their potential benefits and risks.
- Chasteberry may interact with hormonal treatments, and NAC may interact with certain medications, so it is crucial to consult with a healthcare provider before starting either supplement.
- A comprehensive approach including dietary changes, regular exercise, and stress management alongside medical supervision is most effective for managing ovarian cysts.
- The use of Chasteberry and NAC should be individualized, and women should be closely monitored for any adverse effects or interactions with other medications.
In terms of the quality of the evidence, a meta-analysis of double-blind randomized controlled trials found that Vitex agnus-castus extracts were effective in reducing premenstrual syndrome symptoms 3. Another systematic review of clinical trials found that Vitex extracts were beneficial for premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinaemia 1. However, the evidence for the use of Chasteberry and NAC in ovarian cysts is not as strong, and more research is needed to fully understand their potential benefits and risks.