Does a coronary artery calcium (CAC) score involve a computed tomography (CT) scan?

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Coronary Artery Calcium Scoring Uses CT Scanning Technology

Yes, a coronary artery calcium (CAC) score is performed using a computed tomography (CT) scan. The CAC score specifically uses a non-contrast CT scan of the heart to quantify calcium deposits in the coronary arteries 1.

Technical Details of CAC Scoring

CAC scoring involves the following CT-based components:

  • Non-contrast CT scan: CAC scoring is performed using a non-contrast CT scan specifically targeting the heart 1
  • ECG-gating: Ideally, the scan is ECG-gated (synchronized with the heartbeat) to minimize motion artifacts, though non-gated chest CTs can also be used for CAC assessment 1, 2
  • Agatston scoring method: The most common quantification method uses the Agatston score, which calculates calcium burden based on the density and area of calcified lesions 1
  • Visual assessment alternative: When Agatston scoring software isn't available, visual assessment (none, mild, moderate, or heavy/severe) can be used 1

Clinical Applications

CAC scoring via CT is primarily recommended for:

  • Asymptomatic adults aged 40-75 years with intermediate cardiovascular risk (10-20% 10-year ASCVD risk) 3
  • Borderline risk patients (5-10% 10-year risk) with uncertainty about statin therapy 3
  • Low risk patients with concerning features like strong family history of premature ASCVD 3

Interpretation of Results

The CT-derived CAC scores correlate with cardiovascular risk:

  • CAC score of 0: Low risk (<1% annual event rate) 3
  • CAC score of 1-99: Moderate risk 3
  • CAC score of ≥100: High risk 3
  • CAC score of >400: Very high risk 3

Important Distinctions

  • CAC scoring vs. coronary CT angiography (CCTA): CAC scoring uses non-contrast CT, while CCTA requires contrast enhancement 1
  • Dedicated vs. opportunistic CAC scoring: While dedicated CAC scoring is performed with ECG-gated cardiac CT, CAC can also be assessed on routine chest CTs performed for other reasons 2, 4
  • Limitations: CAC scoring only detects calcified plaque and cannot detect non-calcified atherosclerotic plaque 1

Emerging Technologies

Recent advances in CAC scoring technology include:

  • Automated CAC scoring using deep learning algorithms for both dedicated gated coronary CT and routine non-gated chest CTs 5
  • Methods to derive CAC scores from contrast-enhanced CT scans, potentially eliminating the need for separate non-contrast scans 6, 7

It's important to note that while CAC scoring is not recommended for symptomatic patients to rule out coronary artery disease (as CACS = 0 does not exclude obstructive CAD), it remains a valuable tool for risk stratification in asymptomatic individuals 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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