From the Research
Normal International Normalized Ratio (INR) Values
- The normal INR range for patients not on anticoagulants is typically considered to be between 0.9 and 1.1 1.
- However, it's essential to note that the exact normal range may vary slightly depending on the laboratory and the specific testing methods used.
- In patients not on oral anticoagulant therapy, an INR of 1.0 is generally considered normal, with a range of 0.8 to 1.2 being acceptable in some cases 2.
Factors Affecting INR Values
- Various factors can influence INR values, including vitamin K deficiency, liver disease, and the use of certain medications 3.
- In patients with liver disease, INR values may be elevated due to decreased production of clotting factors 3.
- Vitamin K deficiency can also cause elevated INR values, which can be corrected with vitamin K supplementation 3.
Clinical Significance of INR Values
- INR values are crucial in monitoring patients on warfarin therapy, with a target range of 2.0-3.0 being recommended for most patients 4.
- Elevated INR values can increase the risk of bleeding, while low INR values may not provide adequate anticoagulation 5, 4.
- In patients not on anticoagulants, an elevated INR may indicate an underlying coagulopathy or other condition requiring further evaluation 1, 3.